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Page 1
Synthesis and Biological Evaluation of 4'-C,3'-O-Propylene-Linked Bicyclic Nucleosides.
Hatton W, Hunault J, Egorov M, Len C, Pipelier M, Blot V, Silvestre V, Fargeas V, Ané A, McBrayer T, Detorio M, Cho JH, Bourgougnon N, Dubreuil D, Schinazi RF, Lebreton J. Hatton W, et al. Among authors: mcbrayer t. European J Org Chem. 2011 Dec;2011(36):7390-7399. doi: 10.1002/ejoc.201100859. Epub 2011 Oct 28. European J Org Chem. 2011. PMID: 34566488 Free PMC article.
Cannabinoid-Inspired Inhibitors of the SARS-CoV-2 Coronavirus 2'-O-Methyltransferase (2'-O-MTase) Non-Structural Protein (Nsp10-16).
Benjamin MM, Hanna GS, Dickinson CF, Choo YM, Wang X, Downs-Bowen JA, De R, McBrayer TR, Schinazi RF, Nielson SE, Hevel JM, Pandey P, Doerksen RJ, Townsend DM, Zhang J, Ye Z, Wyer S, Bialousow L, Hamann MT. Benjamin MM, et al. Among authors: mcbrayer tr. Molecules. 2024 Oct 28;29(21):5081. doi: 10.3390/molecules29215081. Molecules. 2024. PMID: 39519722 Free PMC article.
Synthesis and biological evaluation of novel peptidomimetic inhibitors of the coronavirus 3C-like protease.
Amblard F, LeCher JC, De R, Zhou S, Liu P, Goh SL, Tao S, Patel D, Downs-Bowen J, Zandi K, Zhang H, Chaudhry G, McBrayer T, Muczynski M, Al-Homoudi A, Engel J, Lan S, Sarafianos SG, Kovari LC, Schinazi RF. Amblard F, et al. Among authors: mcbrayer t. Eur J Med Chem. 2024 Mar 15;268:116263. doi: 10.1016/j.ejmech.2024.116263. Epub 2024 Feb 24. Eur J Med Chem. 2024. PMID: 38432056
Discovery of a 2'-Fluoro,2'-Bromouridine Phosphoramidate Prodrug Exhibiting Anti-Yellow Fever Virus Activity in Culture and in Mice.
LeCher JC, Zandi K, Costa VV, Amblard F, Tao S, Patel D, Lee S, da Silva Santos FR, Goncalves MR, Queroz-Junior CM, Marim FM, Musall K, Goh SL, McBrayer T, Downs-Bowen J, De R, Azadi N, Kohler J, Teixeira MM, Schinazi RF. LeCher JC, et al. Among authors: mcbrayer t. Microorganisms. 2022 Oct 22;10(11):2098. doi: 10.3390/microorganisms10112098. Microorganisms. 2022. PMID: 36363688 Free PMC article.
Comparison of anti-SARS-CoV-2 activity and intracellular metabolism of remdesivir and its parent nucleoside.
Tao S, Zandi K, Bassit L, Ong YT, Verma K, Liu P, Downs-Bowen JA, McBrayer T, LeCher JC, Kohler JJ, Tedbury PR, Kim B, Amblard F, Sarafianos SG, Schinazi RF. Tao S, et al. Among authors: mcbrayer t. Curr Res Pharmacol Drug Discov. 2021;2:100045. doi: 10.1016/j.crphar.2021.100045. Epub 2021 Aug 12. Curr Res Pharmacol Drug Discov. 2021. PMID: 34870151 Free PMC article.
51 results