Griffiths JR - Search Results

1

HIF-1-Independent Mechanisms Regulating Metabolic Adaptation in Hypoxic Cancer Cells.

Lee SH, Golinska M, Griffiths JR. Lee SH, et al. Among authors: griffiths jr. Cells. 2021 Sep 9;10(9):2371. doi: 10.3390/cells10092371. Cells. 2021. PMID: 34572020 Free PMC article. Review.

2

MRI & MRS assessment of the role of the tumour microenvironment in response to therapy.

Bell LK, Ainsworth NL, Lee SH, Griffiths JR. Bell LK, et al. Among authors: griffiths jr. NMR Biomed. 2011 Jul;24(6):612-35. doi: 10.1002/nbm.1720. Epub 2011 May 12. NMR Biomed. 2011. PMID: 21567513 Review.

3

Adaptation to HIF-1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas.

Golinska M, Troy H, Chung YL, McSheehy PM, Mayr M, Yin X, Ly L, Williams KJ, Airley RE, Harris AL, Latigo J, Perumal M, Aboagye EO, Perrett D, Stubbs M, Griffiths JR. Golinska M, et al. Among authors: griffiths jr. BMC Cancer. 2011 May 25;11:198. doi: 10.1186/1471-2407-11-198. BMC Cancer. 2011. PMID: 21612605 Free PMC article.

4

Magnetic resonance spectroscopy of cancer metabolism and response to therapy.

McIntyre DJ, Madhu B, Lee SH, Griffiths JR. McIntyre DJ, et al. Among authors: griffiths jr. Radiat Res. 2012 Apr;177(4):398-435. doi: 10.1667/rr2903.1. Epub 2012 Mar 8. Radiat Res. 2012. PMID: 22401303 Review.

5

Carbonic anhydrase IX is a pH-stat that sets an acidic tumour extracellular pH in vivo.

Lee SH, McIntyre D, Honess D, Hulikova A, Pacheco-Torres J, Cerdán S, Swietach P, Harris AL, Griffiths JR. Lee SH, et al. Among authors: griffiths jr. Br J Cancer. 2018 Aug;119(5):622-630. doi: 10.1038/s41416-018-0216-5. Epub 2018 Sep 12. Br J Cancer. 2018. PMID: 30206370 Free PMC article.

6

How and Why Are Cancers Acidic? Carbonic Anhydrase IX and the Homeostatic Control of Tumour Extracellular pH.

Lee SH, Griffiths JR. Lee SH, et al. Among authors: griffiths jr. Cancers (Basel). 2020 Jun 18;12(6):1616. doi: 10.3390/cancers12061616. Cancers (Basel). 2020. PMID: 32570870 Free PMC article. Review.

7

Survival Pathways of HIF-Deficient Tumour Cells: TCA Inhibition, Peroxisomal Fatty Acid Oxidation Activation and an AMPK-PGC-1α Hypoxia Sensor.

Golinska MA, Stubbs M, Harris AL, Boros LG, Basetti M, McIntyre DJO, Griffiths JR. Golinska MA, et al. Among authors: griffiths jr. Cells. 2022 Nov 14;11(22):3595. doi: 10.3390/cells11223595. Cells. 2022. PMID: 36429023 Free PMC article.

8

Metabolic regulation of the tumour and its microenvironment: The role of Epstein-Barr virus.

Lee SH, Khoo AS, Griffiths JR, Mat Lazim N. Lee SH, et al. Among authors: griffiths jr. Int J Cancer. 2025 Feb 1;156(3):488-498. doi: 10.1002/ijc.35192. Epub 2024 Sep 18. Int J Cancer. 2025. PMID: 39291683 Review.

9

Metabolic changes detected by in vivo magnetic resonance studies of HEPA-1 wild-type tumors and tumors deficient in hypoxia-inducible factor-1beta (HIF-1beta): evidence of an anabolic role for the HIF-1 pathway.

Griffiths JR, McSheehy PM, Robinson SP, Troy H, Chung YL, Leek RD, Williams KJ, Stratford IJ, Harris AL, Stubbs M. Griffiths JR, et al. Cancer Res. 2002 Feb 1;62(3):688-95. Cancer Res. 2002. PMID: 11830521

10

The altered metabolism of tumors: HIF-1 and its role in the Warburg effect.

Stubbs M, Griffiths JR. Stubbs M, et al. Among authors: griffiths jr. Adv Enzyme Regul. 2010;50(1):44-55. doi: 10.1016/j.advenzreg.2009.10.027. Epub 2009 Nov 6. Adv Enzyme Regul. 2010. PMID: 19896967 Review. No abstract available.

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