Conseil G - Search Results

1

The First Cytoplasmic Loop in the Core Structure of the ABCC1 (Multidrug Resistance Protein 1; MRP1) Transporter Contains Multiple Amino Acids Essential for Its Expression.

Conseil G, Cole SPC. Conseil G, et al. Int J Mol Sci. 2021 Sep 8;22(18):9710. doi: 10.3390/ijms22189710. Int J Mol Sci. 2021. PMID: 34575890 Free PMC article.

2

Identification of proline residues in the core cytoplasmic and transmembrane regions of multidrug resistance protein 1 (MRP1/ABCC1) important for transport function, substrate specificity, and nucleotide interactions.

Koike K, Conseil G, Leslie EM, Deeley RG, Cole SP. Koike K, et al. Among authors: conseil g. J Biol Chem. 2004 Mar 26;279(13):12325-36. doi: 10.1074/jbc.M311435200. Epub 2004 Jan 13. J Biol Chem. 2004. PMID: 14722114 Free article.

3

Haimeur A, Conseil G, Deeley RG, Cole SP. Haimeur A, et al. Among authors: conseil g. Curr Drug Metab. 2004 Feb;5(1):21-53. doi: 10.2174/1389200043489199. Curr Drug Metab. 2004. PMID: 14965249 Review.

4

Mutations of charged amino acids in or near the transmembrane helices of the second membrane spanning domain differentially affect the substrate specificity and transport activity of the multidrug resistance protein MRP1 (ABCC1).

Haimeur A, Conseil G, Deeley RG, Cole SP. Haimeur A, et al. Among authors: conseil g. Mol Pharmacol. 2004 Jun;65(6):1375-85. doi: 10.1124/mol.65.6.1375. Mol Pharmacol. 2004. PMID: 15155831

5

Mutational analysis of ionizable residues proximal to the cytoplasmic interface of membrane spanning domain 3 of the multidrug resistance protein, MRP1 (ABCC1): glutamate 1204 is important for both the expression and catalytic activity of the transporter.

Situ D, Haimeur A, Conseil G, Sparks KE, Zhang D, Deeley RG, Cole SP. Situ D, et al. Among authors: conseil g. J Biol Chem. 2004 Sep 10;279(37):38871-80. doi: 10.1074/jbc.M403832200. Epub 2004 Jun 18. J Biol Chem. 2004. PMID: 15208328 Free article.

6

Functional expression of the human breast cancer resistance protein in Pichia pastoris.

Mao Q, Conseil G, Gupta A, Cole SP, Unadkat JD. Mao Q, et al. Among authors: conseil g. Biochem Biophys Res Commun. 2004 Jul 30;320(3):730-7. doi: 10.1016/j.bbrc.2004.06.012. Biochem Biophys Res Commun. 2004. PMID: 15240109

7

Role of two adjacent cytoplasmic tyrosine residues in MRP1 (ABCC1) transport activity and sensitivity to sulfonylureas.

Conseil G, Deeley RG, Cole SP. Conseil G, et al. Biochem Pharmacol. 2005 Feb 1;69(3):451-61. doi: 10.1016/j.bcp.2004.10.014. Epub 2004 Dec 16. Biochem Pharmacol. 2005. PMID: 15652236

8

Polymorphisms of MRP1 (ABCC1) and related ATP-dependent drug transporters.

Conseil G, Deeley RG, Cole SP. Conseil G, et al. Pharmacogenet Genomics. 2005 Aug;15(8):523-33. doi: 10.1097/01.fpc.0000167333.38528.ec. Pharmacogenet Genomics. 2005. PMID: 16006996 Review.

9

Functional importance of three basic residues clustered at the cytosolic interface of transmembrane helix 15 in the multidrug and organic anion transporter MRP1 (ABCC1).

Conseil G, Deeley RG, Cole SP. Conseil G, et al. J Biol Chem. 2006 Jan 6;281(1):43-50. doi: 10.1074/jbc.M510143200. Epub 2005 Oct 17. J Biol Chem. 2006. PMID: 16230346 Free article.

10

Molecular modeling of the human multidrug resistance protein 1 (MRP1/ABCC1).

DeGorter MK, Conseil G, Deeley RG, Campbell RL, Cole SP. DeGorter MK, et al. Among authors: conseil g. Biochem Biophys Res Commun. 2008 Jan 4;365(1):29-34. doi: 10.1016/j.bbrc.2007.10.141. Epub 2007 Oct 31. Biochem Biophys Res Commun. 2008. PMID: 17980150

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