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Page 1
CUE-101, a Novel E7-pHLA-IL2-Fc Fusion Protein, Enhances Tumor Antigen-Specific T-Cell Activation for the Treatment of HPV16-Driven Malignancies.
Quayle SN, Girgis N, Thapa DR, Merazga Z, Kemp MM, Histed A, Zhao F, Moreta M, Ruthardt P, Hulot S, Nelson A, Kraemer LD, Beal DR, Witt L, Ryabin J, Soriano J, Haydock M, Spaulding E, Ross JF, Kiener PA, Almo S, Chaparro R, Seidel R, Suri A, Cemerski S, Pienta KJ, Simcox ME. Quayle SN, et al. Clin Cancer Res. 2020 Apr 15;26(8):1953-1964. doi: 10.1158/1078-0432.CCR-19-3354. Epub 2020 Jan 21. Clin Cancer Res. 2020. PMID: 31964784
In vivo detection of antigen-specific CD8+ T cells by immuno-positron emission tomography.
Woodham AW, Zeigler SH, Zeyang EL, Kolifrath SC, Cheloha RW, Rashidian M, Chaparro RJ, Seidel RD, Garforth SJ, Dearling JL, Mesyngier M, Duddempudi PK, Packard AB, Almo SC, Ploegh HL. Woodham AW, et al. Among authors: chaparro rj. Nat Methods. 2020 Oct;17(10):1025-1032. doi: 10.1038/s41592-020-0934-5. Epub 2020 Sep 14. Nat Methods. 2020. PMID: 32929269 Free PMC article.
Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect.
Brims DR, Qian J, Jarchum I, Mikesh L, Palmieri E, Ramagopal UA, Malashkevich VN, Chaparro RJ, Lund T, Hattori M, Shabanowitz J, Hunt DF, Nathenson SG, Almo SC, Dilorenzo TP. Brims DR, et al. Among authors: chaparro rj. Int Immunol. 2010 Mar;22(3):191-203. doi: 10.1093/intimm/dxp127. Epub 2010 Jan 21. Int Immunol. 2010. PMID: 20093428 Free PMC article.
Glucagon-reactive islet-infiltrating CD8 T cells in NOD mice.
Mukherjee G, Chaparro RJ, Schloss J, Smith C, Bando CD, DiLorenzo TP. Mukherjee G, et al. Among authors: chaparro rj. Immunology. 2015 Apr;144(4):631-40. doi: 10.1111/imm.12415. Immunology. 2015. PMID: 25333865 Free PMC article.
Nonobese diabetic mice express aspects of both type 1 and type 2 diabetes.
Chaparro RJ, Konigshofer Y, Beilhack GF, Shizuru JA, McDevitt HO, Chien YH. Chaparro RJ, et al. Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12475-80. doi: 10.1073/pnas.0604317103. Epub 2006 Aug 8. Proc Natl Acad Sci U S A. 2006. PMID: 16895987 Free PMC article.