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Neurotoxicity with high-dose disulfiram and vorinostat used for HIV latency reversal.
McMahon JH, Evans VA, Lau JSY, Symons J, Zerbato JM, Chang J, Solomon A, Tennakoon S, Dantanarayana A, Hagenauer M, Lee S, Palmer S, Fisher K, Bumpus N, Heck CJS, Burger D, Wu G, Zuck P, Howell BJ, Zetterberg HH, Blennow K, Gisslen M, Rasmussen TA, Lewin SR. McMahon JH, et al. Among authors: howell bj. AIDS. 2022 Jan 1;36(1):75-82. doi: 10.1097/QAD.0000000000003091. AIDS. 2022. PMID: 34586085
HDAC inhibition induces HIV-1 protein and enables immune-based clearance following latency reversal.
Wu G, Swanson M, Talla A, Graham D, Strizki J, Gorman D, Barnard RJ, Blair W, Søgaard OS, Tolstrup M, Østergaard L, Rasmussen TA, Sekaly RP, Archin NM, Margolis DM, Hazuda DJ, Howell BJ. Wu G, et al. Among authors: howell bj. JCI Insight. 2017 Aug 17;2(16):e92901. doi: 10.1172/jci.insight.92901. eCollection 2017 Aug 17. JCI Insight. 2017. PMID: 28814661 Free PMC article.
Ultrasensitive Immunoassay for Simian Immunodeficiency Virus p27CA.
Swanstrom AE, Gorelick RJ, Wu G, Howell B, Vijayagopalan A, Shoemaker R, Oswald K, Datta SA, Keele BF, Del Prete GQ, Chertova E, Bess JW Jr, Lifson JD. Swanstrom AE, et al. AIDS Res Hum Retroviruses. 2018 Nov;34(11):993-1001. doi: 10.1089/AID.2018.0075. Epub 2018 Jul 10. AIDS Res Hum Retroviruses. 2018. PMID: 29869527 Free PMC article.
Antiretroviral therapy alone versus antiretroviral therapy with a kick and kill approach, on measures of the HIV reservoir in participants with recent HIV infection (the RIVER trial): a phase 2, randomised trial.
Fidler S, Stöhr W, Pace M, Dorrell L, Lever A, Pett S, Kinloch-de Loes S, Fox J, Clarke A, Nelson M, Thornhill J, Khan M, Fun A, Bandara M, Kelly D, Kopycinski J, Hanke T, Yang H, Bennett R, Johnson M, Howell B, Barnard R, Wu G, Kaye S, Wills M, Babiker A, Frater J; RIVER trial study group. Fidler S, et al. Lancet. 2020 Mar 14;395(10227):888-898. doi: 10.1016/S0140-6736(19)32990-3. Epub 2020 Feb 19. Lancet. 2020. PMID: 32085823 Clinical Trial.
[No title available]
[No authors listed] [No authors listed] PMID: 32556126
Intact Human Immunodeficiency Virus (HIV) Reservoir Estimated by the Intact Proviral DNA Assay Correlates With Levels of Total and Integrated DNA in the Blood During Suppressive Antiretroviral Therapy.
Papasavvas E, Azzoni L, Ross BN, Fair M, Yuan Z, Gyampoh K, Mackiewicz A, Sciorillo AC, Pagliuzza A, Lada SM, Wu G, Goh SL, Bahnck-Teets C, Holder DJ, Zuck PD, Damra M, Lynn KM, Tebas P, Mounzer K, Kostman JR, Abdel-Mohsen M, Richman D, Chomont N, Howell BJ, Montaner LJ. Papasavvas E, et al. Among authors: howell bj. Clin Infect Dis. 2021 Feb 1;72(3):495-498. doi: 10.1093/cid/ciaa809. Clin Infect Dis. 2021. PMID: 33527127 Free PMC article.
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