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Recombinant Desmodus rotundus salivary plasminogen activator crosses the blood-brain barrier through a low-density lipoprotein receptor-related protein-dependent mechanism without exerting neurotoxic effects.
López-Atalaya JP, Roussel BD, Ali C, Maubert E, Petersen KU, Berezowski V, Cecchelli R, Orset C, Vivien D. López-Atalaya JP, et al. Among authors: vivien d. Stroke. 2007 Mar;38(3):1036-43. doi: 10.1161/01.STR.0000258100.04923.84. Stroke. 2007. PMID: 17325305
Mouse model of in situ thromboembolic stroke and reperfusion.
Orset C, Macrez R, Young AR, Panthou D, Angles-Cano E, Maubert E, Agin V, Vivien D. Orset C, et al. Among authors: vivien d. Stroke. 2007 Oct;38(10):2771-8. doi: 10.1161/STROKEAHA.107.487520. Epub 2007 Aug 16. Stroke. 2007. PMID: 17702959
Antibodies preventing the interaction of tissue-type plasminogen activator with N-methyl-D-aspartate receptors reduce stroke damages and extend the therapeutic window of thrombolysis.
Macrez R, Obiang P, Gauberti M, Roussel B, Baron A, Parcq J, Cassé F, Hommet Y, Orset C, Agin V, Bezin L, Berrocoso TG, Petersen KU, Montaner J, Maubert E, Vivien D, Ali C. Macrez R, et al. Among authors: vivien d. Stroke. 2011 Aug;42(8):2315-22. doi: 10.1161/STROKEAHA.110.606293. Epub 2011 Jun 16. Stroke. 2011. PMID: 21680906
Memantine improves safety of thrombolysis for stroke.
Montagne A, Hébert M, Jullienne A, Lesept F, Le Béhot A, Louessard M, Gauberti M, Orset C, Ali C, Agin V, Maubert E, Vivien D. Montagne A, et al. Among authors: vivien d. Stroke. 2012 Oct;43(10):2774-81. doi: 10.1161/STROKEAHA.112.669374. Epub 2012 Aug 9. Stroke. 2012. PMID: 22879098
358 results