Orr C - Search Results

1

Loss of balance between protective and pro-inflammatory synovial tissue T-cell polyfunctionality predates clinical onset of rheumatoid arthritis.

Floudas A, Neto N, Orr C, Canavan M, Gallagher P, Hurson C, Monaghan MG, Nagpar S, Mullan RH, Veale DJ, Fearon U. Floudas A, et al. Among authors: orr c. Ann Rheum Dis. 2022 Feb;81(2):193-205. doi: 10.1136/annrheumdis-2021-220458. Epub 2021 Oct 1. Ann Rheum Dis. 2022. PMID: 34598926

2

Comparison of remission criteria in a tumour necrosis factor inhibitor treated rheumatoid arthritis longitudinal cohort: patient global health is a confounder.

Balogh E, Madruga Dias J, Orr C, Mullan R, Harty L, FitzGerald O, Gallagher P, Molloy M, O'Flynn E, Kelly A, Minnock P, O'Neill M, Moore L, Murray M, Fearon U, Veale DJ. Balogh E, et al. Among authors: orr c. Arthritis Res Ther. 2013 Dec 24;15(6):R221. doi: 10.1186/ar4421. Arthritis Res Ther. 2013. PMID: 24365061 Free PMC article.

3

Is there a need for new agents with novel mechanisms of action in psoriatic arthritis?

Orr C, Veale DJ. Orr C, et al. Ann Rheum Dis. 2014 Jun;73(6):951-3. doi: 10.1136/annrheumdis-2013-204934. Ann Rheum Dis. 2014. PMID: 24790066 No abstract available.

4

Toll-like receptor 2 (TLR2) induces migration and invasive mechanisms in rheumatoid arthritis.

McGarry T, Veale DJ, Gao W, Orr C, Fearon U, Connolly M. McGarry T, et al. Among authors: orr c. Arthritis Res Ther. 2015 Jun 9;17(1):153. doi: 10.1186/s13075-015-0664-8. Arthritis Res Ther. 2015. PMID: 26055925 Free PMC article.

5

Polyfunctional, Pathogenic CD161+ Th17 Lineage Cells Are Resistant to Regulatory T Cell-Mediated Suppression in the Context of Autoimmunity.

Basdeo SA, Moran B, Cluxton D, Canavan M, McCormick J, Connolly M, Orr C, Mills KH, Veale DJ, Fearon U, Fletcher JM. Basdeo SA, et al. Among authors: orr c. J Immunol. 2015 Jul 15;195(2):528-40. doi: 10.4049/jimmunol.1402990. Epub 2015 Jun 10. J Immunol. 2015. PMID: 26062995

6

Tofacitinib regulates synovial inflammation in psoriatic arthritis, inhibiting STAT activation and induction of negative feedback inhibitors.

Gao W, McGarry T, Orr C, McCormick J, Veale DJ, Fearon U. Gao W, et al. Among authors: orr c. Ann Rheum Dis. 2016 Jan;75(1):311-5. doi: 10.1136/annrheumdis-2014-207201. Epub 2015 Sep 9. Ann Rheum Dis. 2016. PMID: 26353790 Free PMC article.

7

Success Rate and Utility of Ultrasound-guided Synovial Biopsies in Clinical Practice.

Najm A, Orr C, Heymann MF, Bart G, Veale DJ, Le Goff B. Najm A, et al. Among authors: orr c. J Rheumatol. 2016 Dec;43(12):2113-2119. doi: 10.3899/jrheum.151441. Epub 2016 Oct 15. J Rheumatol. 2016. PMID: 27744399 Free article.

8

Ex-Th17 (Nonclassical Th1) Cells Are Functionally Distinct from Classical Th1 and Th17 Cells and Are Not Constrained by Regulatory T Cells.

Basdeo SA, Cluxton D, Sulaimani J, Moran B, Canavan M, Orr C, Veale DJ, Fearon U, Fletcher JM. Basdeo SA, et al. Among authors: orr c. J Immunol. 2017 Mar 15;198(6):2249-2259. doi: 10.4049/jimmunol.1600737. Epub 2017 Feb 6. J Immunol. 2017. PMID: 28167631

9

Resolution of TLR2-induced inflammation through manipulation of metabolic pathways in Rheumatoid Arthritis.

McGarry T, Biniecka M, Gao W, Cluxton D, Canavan M, Wade S, Wade S, Gallagher L, Orr C, Veale DJ, Fearon U. McGarry T, et al. Among authors: orr c. Sci Rep. 2017 Feb 22;7:43165. doi: 10.1038/srep43165. Sci Rep. 2017. PMID: 28225071 Free PMC article.

10

Brief Report: Genetic Variation of the α₁ -Antitrypsin Gene Is Associated With Increased Autoantibody Production in Rheumatoid Arthritis.

McCarthy C, Orr C, Fee LT, Carroll TP, Dunlea DM, Hunt DJL, Dunne E, O'Connell P, McCarthy G, Kenny D, Fearon U, Veale DJ, Reeves EP, McElvaney NG. McCarthy C, et al. Among authors: orr c. Arthritis Rheumatol. 2017 Aug;69(8):1576-1579. doi: 10.1002/art.40127. Epub 2017 Jun 26. Arthritis Rheumatol. 2017. PMID: 28409899

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