Kempkes B - Search Results

1

PLK1-dependent phosphorylation restrains EBNA2 activity and lymphomagenesis in EBV-infected mice.

Zhang X, Schuhmachers P, Mourão A, Giansanti P, Murer A, Thumann S, Kuklik-Roos C, Beer S, Hauck SM, Hammerschmidt W, Küppers R, Kuster B, Raab M, Strebhardt K, Sattler M, Münz C, Kempkes B. Zhang X, et al. Among authors: kempkes b. EMBO Rep. 2021 Dec 6;22(12):e53007. doi: 10.15252/embr.202153007. Epub 2021 Oct 4. EMBO Rep. 2021. PMID: 34605140 Free PMC article.

2

EBNA2-EBF1 complexes promote MYC expression and metabolic processes driving S-phase progression of Epstein-Barr virus-infected B cells.

Beer S, Wange LE, Zhang X, Kuklik-Roos C, Enard W, Hammerschmidt W, Scialdone A, Kempkes B. Beer S, et al. Among authors: kempkes b. Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2200512119. doi: 10.1073/pnas.2200512119. Epub 2022 Jul 20. Proc Natl Acad Sci U S A. 2022. PMID: 35857872 Free PMC article.

3

The CR4 region of EBNA2 confers viability of Epstein-Barr virus-transformed B cells by CBF1-independent signalling.

Grabusic K, Maier S, Hartmann A, Mantik A, Hammerschmidt W, Kempkes B. Grabusic K, et al. Among authors: kempkes b. J Gen Virol. 2006 Nov;87(Pt 11):3169-3176. doi: 10.1099/vir.0.82105-0. J Gen Virol. 2006. PMID: 17030849

4

The EBNA-2 N-Terminal Transactivation Domain Folds into a Dimeric Structure Required for Target Gene Activation.

Friberg A, Thumann S, Hennig J, Zou P, Nössner E, Ling PD, Sattler M, Kempkes B. Friberg A, et al. Among authors: kempkes b. PLoS Pathog. 2015 May 29;11(5):e1004910. doi: 10.1371/journal.ppat.1004910. eCollection 2015 May. PLoS Pathog. 2015. PMID: 26024477 Free PMC article.

5

EBF1 binds to EBNA2 and promotes the assembly of EBNA2 chromatin complexes in B cells.

Glaser LV, Rieger S, Thumann S, Beer S, Kuklik-Roos C, Martin DE, Maier KC, Harth-Hertle ML, Grüning B, Backofen R, Krebs S, Blum H, Zimmer R, Erhard F, Kempkes B. Glaser LV, et al. Among authors: kempkes b. PLoS Pathog. 2017 Oct 2;13(10):e1006664. doi: 10.1371/journal.ppat.1006664. eCollection 2017 Oct. PLoS Pathog. 2017. PMID: 28968461 Free PMC article.

6

B-cell proliferation and induction of early G1-regulating proteins by Epstein-Barr virus mutants conditional for EBNA2.

Kempkes B, Spitkovsky D, Jansen-Dürr P, Ellwart JW, Kremmer E, Delecluse HJ, Rottenberger C, Bornkamm GW, Hammerschmidt W. Kempkes B, et al. EMBO J. 1995 Jan 3;14(1):88-96. doi: 10.1002/j.1460-2075.1995.tb06978.x. EMBO J. 1995. PMID: 7828599 Free PMC article.

7

A somatic knockout of CBF1 in a human B-cell line reveals that induction of CD21 and CCR7 by EBNA-2 is strictly CBF1 dependent and that downregulation of immunoglobulin M is partially CBF1 independent.

Maier S, Santak M, Mantik A, Grabusic K, Kremmer E, Hammerschmidt W, Kempkes B. Maier S, et al. Among authors: kempkes b. J Virol. 2005 Jul;79(14):8784-92. doi: 10.1128/JVI.79.14.8784-8792.2005. J Virol. 2005. PMID: 15994772 Free PMC article.

8

Epstein-Barr virus nuclear antigen 2 (EBNA2)-oestrogen receptor fusion proteins complement the EBNA2-deficient Epstein-Barr virus strain P3HR1 in transformation of primary B cells but suppress growth of human B cell lymphoma lines.

Kempkes B, Zimber-Strobl U, Eissner G, Pawlita M, Falk M, Hammerschmidt W, Bornkamm GW. Kempkes B, et al. J Gen Virol. 1996 Feb;77 ( Pt 2 ):227-37. doi: 10.1099/0022-1317-77-2-227. J Gen Virol. 1996. PMID: 8627226

9

EBNA2 and Its Coactivator EBNA-LP.

Kempkes B, Ling PD. Kempkes B, et al. Curr Top Microbiol Immunol. 2015;391:35-59. doi: 10.1007/978-3-319-22834-1_2. Curr Top Microbiol Immunol. 2015. PMID: 26428371 Review.

10

Immortalization of human primary B lymphocytes in vitro with DNA.

Kempkes B, Pich D, Zeidler R, Hammerschmidt W. Kempkes B, et al. Proc Natl Acad Sci U S A. 1995 Jun 20;92(13):5875-9. doi: 10.1073/pnas.92.13.5875. Proc Natl Acad Sci U S A. 1995. PMID: 7597045 Free PMC article.

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