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Page 1
Inhibiting casein kinase 2 sensitizes acute lymphoblastic leukemia cells to venetoclax via MCL1 degradation.
Lázaro-Navarro J, Pimentel-Gutiérrez HJ, Gauert A, Hagemann AIH, Eisenschmid J, Gökbuget N, Vick B, Jeremias I, Seyfried F, Meyer LH, Debatin KM, Richer K, Bultman M, Neumann M, Hänzelmann S, Serve H, Astrahantseff K, Rieger MA, Eckert C, Baldus CD, Bastian L. Lázaro-Navarro J, et al. Among authors: hanzelmann s. Blood Adv. 2021 Dec 28;5(24):5501-5506. doi: 10.1182/bloodadvances.2021004513. Blood Adv. 2021. PMID: 34610112 Free PMC article. No abstract available.
PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia.
Bastian L, Schroeder MP, Eckert C, Schlee C, Tanchez JO, Kämpf S, Wagner DL, Schulze V, Isaakidis K, Lázaro-Navarro J, Hänzelmann S, James AR, Ekici A, Burmeister T, Schwartz S, Schrappe M, Horstmann M, Vosberg S, Krebs S, Blum H, Hecht J, Greif PA, Rieger MA, Brüggemann M, Gökbuget N, Neumann M, Baldus CD. Bastian L, et al. Among authors: hanzelmann s. Leukemia. 2019 Aug;33(8):1895-1909. doi: 10.1038/s41375-019-0430-z. Epub 2019 Mar 6. Leukemia. 2019. PMID: 30842609
An alternative CYB5A transcript is expressed in aneuploid ALL and enriched in relapse.
Bartsch L, Schroeder MP, Hänzelmann S, Bastian L, Lázaro-Navarro J, Schlee C, Tanchez JO, Schulze V, Isaakidis K, Rieger MA, Gökbuget N, Eckert C, Serve H, Horstmann M, Schrappe M, Brüggemann M, Baldus CD, Neumann M. Bartsch L, et al. Among authors: hanzelmann s. BMC Genom Data. 2022 Apr 18;23(1):30. doi: 10.1186/s12863-022-01041-1. BMC Genom Data. 2022. PMID: 35436854 Free PMC article.
UBTF::ATXN7L3 gene fusion defines novel B cell precursor ALL subtype with CDX2 expression and need for intensified treatment.
Bastian L, Hartmann AM, Beder T, Hänzelmann S, Kässens J, Bultmann M, Hoeppner MP, Franzenburg S, Wittig M, Franke A, Nagel I, Spielmann M, Reimer N, Busch H, Schwartz S, Steffen B, Viardot A, Döhner K, Kondakci M, Wulf G, Wendelin K, Renzelmann A, Kiani A, Trautmann H, Neumann M, Gökbuget N, Brüggemann M, Baldus CD. Bastian L, et al. Among authors: hanzelmann s. Leukemia. 2022 Jun;36(6):1676-1680. doi: 10.1038/s41375-022-01557-6. Epub 2022 Apr 9. Leukemia. 2022. PMID: 35397658 Free PMC article. No abstract available.
Potential and pitfalls of whole transcriptome-based immunogenetic marker identification in acute lymphoblastic leukemia; a EuroMRD and EuroClonality-NGS Working Group study.
van der Velden VHJ, Brüggemann M, Cazzaniga G, Scheijen B, Tops B, Trka J, Pal K, Hänzelmann S, Fazio G, Songia S, Langerak AW, Darzentas N; EuroMRD; EuroClonality-NGS Working Group. van der Velden VHJ, et al. Among authors: hanzelmann s. Leukemia. 2021 Mar;35(3):924-928. doi: 10.1038/s41375-021-01154-z. Epub 2021 Feb 19. Leukemia. 2021. PMID: 33608635 Free PMC article. No abstract available.
CDKN2A loss and PIK3CA mutation in myoepithelial-like metaplastic breast cancer.
Bartels S, van Luttikhuizen JL, Christgen M, Mägel L, Luft A, Hänzelmann S, Lehmann U, Schlegelberger B, Leo F, Steinemann D, Kreipe H. Bartels S, et al. Among authors: hanzelmann s. J Pathol. 2018 Jul;245(3):373-383. doi: 10.1002/path.5091. Epub 2018 May 28. J Pathol. 2018. PMID: 29708279
Mtss1 is a critical epigenetically regulated tumor suppressor in CML.
Schemionek M, Herrmann O, Reher MM, Chatain N, Schubert C, Costa IG, Hänzelmann S, Gusmao EG, Kintsler S, Braunschweig T, Hamilton A, Helgason GV, Copland M, Schwab A, Müller-Tidow C, Li S, Holyoake TL, Brümmendorf TH, Koschmieder S. Schemionek M, et al. Among authors: hanzelmann s. Leukemia. 2016 Apr;30(4):823-32. doi: 10.1038/leu.2015.329. Epub 2015 Dec 1. Leukemia. 2016. PMID: 26621336 Free article.
Epigenetic program and transcription factor circuitry of dendritic cell development.
Lin Q, Chauvistré H, Costa IG, Gusmao EG, Mitzka S, Hänzelmann S, Baying B, Klisch T, Moriggl R, Hennuy B, Smeets H, Hoffmann K, Benes V, Seré K, Zenke M. Lin Q, et al. Among authors: hanzelmann s. Nucleic Acids Res. 2015 Nov 16;43(20):9680-93. doi: 10.1093/nar/gkv1056. Epub 2015 Oct 17. Nucleic Acids Res. 2015. PMID: 26476451 Free PMC article.
Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes.
Axelsson AS, Mahdi T, Nenonen HA, Singh T, Hänzelmann S, Wendt A, Bagge A, Reinbothe TM, Millstein J, Yang X, Zhang B, Gusmao EG, Shu L, Szabat M, Tang Y, Wang J, Salö S, Eliasson L, Artner I, Fex M, Johnson JD, Wollheim CB, Derry JMJ, Mecham B, Spégel P, Mulder H, Costa IG, Zhang E, Rosengren AH. Axelsson AS, et al. Among authors: hanzelmann s. Nat Commun. 2017 Jun 6;8:15652. doi: 10.1038/ncomms15652. Nat Commun. 2017. PMID: 28585545 Free PMC article.
33 results