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The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation.
Pras A, Houben B, Aprile FA, Seinstra R, Gallardo R, Janssen L, Hogewerf W, Gallrein C, De Vleeschouwer M, Mata-Cabana A, Koopman M, Stroo E, de Vries M, Louise Edwards S, Kirstein J, Vendruscolo M, Falsone SF, Rousseau F, Schymkowitz J, Nollen EAA. Pras A, et al. Among authors: seinstra r. EMBO J. 2021 Nov 2;40(21):e107568. doi: 10.15252/embj.2020107568. Epub 2021 Oct 7. EMBO J. 2021. PMID: 34617299 Free PMC article.
Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation.
van der Goot AT, Zhu W, Vázquez-Manrique RP, Seinstra RI, Dettmer K, Michels H, Farina F, Krijnen J, Melki R, Buijsman RC, Ruiz Silva M, Thijssen KL, Kema IP, Neri C, Oefner PJ, Nollen EA. van der Goot AT, et al. Among authors: seinstra ri. Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):14912-7. doi: 10.1073/pnas.1203083109. Epub 2012 Aug 27. Proc Natl Acad Sci U S A. 2012. PMID: 22927396 Free PMC article.
Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease.
Perni M, van der Goot A, Limbocker R, van Ham TJ, Aprile FA, Xu CK, Flagmeier P, Thijssen K, Sormanni P, Fusco G, Chen SW, Challa PK, Kirkegaard JB, Laine RF, Ma KY, Müller MBD, Sinnige T, Kumita JR, Cohen SIA, Seinstra R, Kaminski Schierle GS, Kaminski CF, Barbut D, De Simone A, Knowles TPJ, Zasloff M, Nollen EAA, Vendruscolo M, Dobson CM. Perni M, et al. Among authors: seinstra r. Front Cell Dev Biol. 2021 Mar 22;9:552549. doi: 10.3389/fcell.2021.552549. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33829010 Free PMC article.
17 results