Abu-Serie MM - Search Results

1

Halting Tumor Progression via Novel Non-Hydroxamate Triazole-Based Mannich Bases MMP-2/9 Inhibitors; Design, Microwave-Assisted Synthesis, and Biological Evaluation.

Albelwi FF, Teleb M, Abu-Serie MM, Moaty MNAA, Alsubaie MS, Zakaria MA, El Kilany Y, Aouad MR, Hagar M, Rezki N. Albelwi FF, et al. Int J Mol Sci. 2021 Sep 25;22(19):10324. doi: 10.3390/ijms221910324. Int J Mol Sci. 2021. PMID: 34638665 Free PMC article.

2

Synthesis of piperazine-based thiazolidinones as VEGFR2 tyrosine kinase inhibitors inducing apoptosis.

El-Miligy MM, Abd El Razik HA, Abu-Serie MM. El-Miligy MM, et al. Future Med Chem. 2017 Oct;9(15):1709-1729. doi: 10.4155/fmc-2017-0072. Epub 2017 Sep 19. Future Med Chem. 2017. PMID: 28925739

3

Purines and triazolo[4,3-e]purines containing pyrazole moiety as potential anticancer and antioxidant agents.

Shaaban OG, Abd El Razik HA, A Shams El-Dine SE, Ashour FA, El-Tombary AA, Afifi OS, Abu-Serie MM. Shaaban OG, et al. Future Med Chem. 2018 Jun 1;10(12):1449-1464. doi: 10.4155/fmc-2017-0227. Epub 2018 May 23. Future Med Chem. 2018. PMID: 29788781

4

Design, synthesis and biological evaluation of novel α-acyloxy carboxamides via Passerini reaction as caspase 3/7 activators.

Salah Ayoup M, Wahby Y, Abdel-Hamid H, Ramadan ES, Teleb M, Abu-Serie MM, Noby A. Salah Ayoup M, et al. Eur J Med Chem. 2019 Apr 15;168:340-356. doi: 10.1016/j.ejmech.2019.02.051. Epub 2019 Feb 22. Eur J Med Chem. 2019. PMID: 30826510

5

Synthesis and biological evaluation of purine-pyrazole hybrids incorporating thiazole, thiazolidinone or rhodanine moiety as 15-LOX inhibitors endowed with anticancer and antioxidant potential.

Afifi OS, Shaaban OG, Abd El Razik HA, Shams El-Dine SEA, Ashour FA, El-Tombary AA, Abu-Serie MM. Afifi OS, et al. Bioorg Chem. 2019 Jun;87:821-837. doi: 10.1016/j.bioorg.2019.03.076. Epub 2019 Apr 1. Bioorg Chem. 2019. PMID: 30999135

6

Dual VEGFR-2/PIM-1 kinase inhibition towards surmounting the resistance to antiangiogenic agents via hybrid pyridine and thienopyridine-based scaffolds: Design, synthesis and biological evaluation.

Rizk OH, Teleb M, Abu-Serie MM, Shaaban OG. Rizk OH, et al. Bioorg Chem. 2019 Nov;92:103189. doi: 10.1016/j.bioorg.2019.103189. Epub 2019 Aug 8. Bioorg Chem. 2019. PMID: 31473473

7

Battle tactics against MMP-9; discovery of novel non-hydroxamate MMP-9 inhibitors endowed with PI3K/AKT signaling attenuation and caspase 3/7 activation via Ugi bis-amide synthesis.

Ayoup MS, Fouad MA, Abdel-Hamid H, Ramadan ES, Abu-Serie MM, Noby A, Teleb M. Ayoup MS, et al. Eur J Med Chem. 2020 Jan 15;186:111875. doi: 10.1016/j.ejmech.2019.111875. Epub 2019 Nov 10. Eur J Med Chem. 2020. PMID: 31740054

8

Structure-based design and optimization of pyrimidine- and 1,2,4-triazolo[4,3-a]pyrimidine-based matrix metalloproteinase-10/13 inhibitors via Dimroth rearrangement towards targeted polypharmacology.

El Ashry ESH, Awad LF, Teleb M, Ibrahim NA, Abu-Serie MM, Abd Al Moaty MN. El Ashry ESH, et al. Bioorg Chem. 2020 Mar;96:103616. doi: 10.1016/j.bioorg.2020.103616. Epub 2020 Jan 25. Bioorg Chem. 2020. PMID: 32032847

9

Beyond direct Nrf2 activation; reinvestigating 1,2,4-oxadiazole scaffold as a master key unlocking the antioxidant cellular machinery for cancer therapy.

Ayoup MS, Abu-Serie MM, Abdel-Hamid H, Teleb M. Ayoup MS, et al. Eur J Med Chem. 2021 Aug 5;220:113475. doi: 10.1016/j.ejmech.2021.113475. Epub 2021 Apr 16. Eur J Med Chem. 2021. PMID: 33901898

10

Nitrofurazone repurposing towards design and synthesis of novel apoptotic-dependent anticancer and antimicrobial agents: Biological evaluation, kinetic studies and molecular modeling.

El-Wakil MH, Meheissen MA, Abu-Serie MM. El-Wakil MH, et al. Bioorg Chem. 2021 Aug;113:104971. doi: 10.1016/j.bioorg.2021.104971. Epub 2021 May 7. Bioorg Chem. 2021. PMID: 34051413

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