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Genetic Engineering in Combination with Semi-Synthesis Leads to a New Route for Gram-Scale Production of the Immunosuppressive Natural Product Brasilicardin A.
Botas A, Eitel M, Schwarz PN, Buchmann A, Costales P, Núñez LE, Cortés J, Morís F, Krawiec M, Wolański M, Gust B, Rodriguez M, Fischer WN, Jandeleit B, Zakrzewska-Czerwińska J, Wohlleben W, Stegmann E, Koch P, Méndez C, Gross H. Botas A, et al. Among authors: rodriguez m. Angew Chem Int Ed Engl. 2021 Jun 7;60(24):13536-13541. doi: 10.1002/anie.202015852. Epub 2021 May 1. Angew Chem Int Ed Engl. 2021. PMID: 33768597 Free PMC article.
A Novel Brain-Permeant Chemotherapeutic Agent for the Treatment of Brain Metastasis in Triple-Negative Breast Cancer.
Deng J, Chernikova SB, Wang Y, Rodriguez ML, Andersen SJ, Umeh-Garcia MC, Godfrey BO, Ahmadian SS, Fischer WN, Koller KJ, Jandeleit B, Ringold GM, Gephart MH. Deng J, et al. Among authors: rodriguez ml. Mol Cancer Ther. 2021 Nov;20(11):2110-2116. doi: 10.1158/1535-7163.MCT-21-0140. Epub 2021 Oct 11. Mol Cancer Ther. 2021. PMID: 34635566 Free PMC article.
Successful anti-tumor effects with two novel bifunctional chemotherapeutic compounds that combine a LAT1 substrate with cytotoxic moieties in aggressive T-cell lymphomas.
Murga-Zamalloa C, Webb S, Reneau J, Zevallos A, Danos-Diaz P, Perez-Silos V, Rodriguez M, Gao G, Fischer WN, Jandeleit B, Wilcox R. Murga-Zamalloa C, et al. Among authors: rodriguez m. Leuk Res Rep. 2023 Nov 22;21:100398. doi: 10.1016/j.lrr.2023.100398. eCollection 2024. Leuk Res Rep. 2023. PMID: 38192502 Free PMC article.
Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer.
Gross MI, Demo SD, Dennison JB, Chen L, Chernov-Rogan T, Goyal B, Janes JR, Laidig GJ, Lewis ER, Li J, Mackinnon AL, Parlati F, Rodriguez ML, Shwonek PJ, Sjogren EB, Stanton TF, Wang T, Yang J, Zhao F, Bennett MK. Gross MI, et al. Among authors: rodriguez ml. Mol Cancer Ther. 2014 Apr;13(4):890-901. doi: 10.1158/1535-7163.MCT-13-0870. Epub 2014 Feb 12. Mol Cancer Ther. 2014. PMID: 24523301
Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer.
Momcilovic M, Bailey ST, Lee JT, Fishbein MC, Magyar C, Braas D, Graeber T, Jackson NJ, Czernin J, Emberley E, Gross M, Janes J, Mackinnon A, Pan A, Rodriguez M, Works M, Zhang W, Parlati F, Demo S, Garon E, Krysan K, Walser TC, Dubinett SM, Sadeghi S, Christofk HR, Shackelford DB. Momcilovic M, et al. Among authors: rodriguez m. Cell Rep. 2017 Jan 17;18(3):601-610. doi: 10.1016/j.celrep.2016.12.061. Cell Rep. 2017. PMID: 28099841 Free PMC article.
Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironment.
Steggerda SM, Bennett MK, Chen J, Emberley E, Huang T, Janes JR, Li W, MacKinnon AL, Makkouk A, Marguier G, Murray PJ, Neou S, Pan A, Parlati F, Rodriguez MLM, Van de Velde LA, Wang T, Works M, Zhang J, Zhang W, Gross MI. Steggerda SM, et al. Among authors: rodriguez mlm. J Immunother Cancer. 2017 Dec 19;5(1):101. doi: 10.1186/s40425-017-0308-4. J Immunother Cancer. 2017. PMID: 29254508 Free PMC article.
Large-scale evaluation of outcomes after a genetic diagnosis in children with severe developmental disorders.
Copeland H, Low KJ, Wynn SL, Ahmed A, Arthur V, Balasubramanian M, Bennett K, Berg J, Bertoli M, Bryson L, Bucknall C, Campbell J, Chandler K, Chauhan J, Clarkson A, Coles R, Conti H, Costello P, Coupar T, Craig A, Dean J, Dillon A, Dixit A, Drew K, Eason J, Forzano F, Foulds N, Gardham A, Ghali N, Green A, Hanna W, Harrison R, Hegarty M, Higgs J, Holder M, Irving R, Jain V, Johnson K, Jolley R, Jones WD, Jones G, Joss S, Kalinauskiene R, Kanani F, Kavanagh K, Khan M, Khan N, Kivuva E, Lahiri N, Lakhani N, Lampe A, Lynch SA, Mansour S, Marsden A, Massey H, McKee S, Mohammed S, Naik S, Nesarajah M, Newbury-Ecob R, Osborne F, Parker MJ, Patterson J, Pottinger C, Prapa M, Prescott K, Quinn S, Radley JA, Robart S, Ross A, Rosti G, Sansbury FH, Sarkar A, Searle C, Shannon N, Shears D, Smithson S, Stewart H, Suri M, Tadros S, Theobald R, Thomas R, Tsoulaki O, Vasudevan P, Rodriguez MV, Vittery E, Whyte S, Woods E, Wright T, Zocche D, Firth HV, Wright CF; DDD Study28. Copeland H, et al. Among authors: rodriguez mv. Genet Med Open. 2024 Oct 14;2:101864. doi: 10.1016/j.gimo.2024.101864. eCollection 2024. Genet Med Open. 2024. PMID: 39822267 Free PMC article.
Coronally Advanced Flap with a Xenogeneic Collagen Matrix or a rhPDGF-BB-regenerative approach for Bilateral Multiple Gingival Recessions: A Split-mouth Clinical Feasibility Study.
Barootchi S, Rodriguez MV, Sabri H, Manouchehri N, Barootchi E, Wang HL, Tavelli L. Barootchi S, et al. Among authors: rodriguez mv. Int J Periodontics Restorative Dent. 2025 Jan 14;0(0):1-28. doi: 10.11607/prd.7503. Online ahead of print. Int J Periodontics Restorative Dent. 2025. PMID: 39808536
8,741 results