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Page 1
mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern.
Goel RR, Painter MM, Apostolidis SA, Mathew D, Meng W, Rosenfeld AM, Lundgreen KA, Reynaldi A, Khoury DS, Pattekar A, Gouma S, Kuri-Cervantes L, Hicks P, Dysinger S, Hicks A, Sharma H, Herring S, Korte S, Baxter AE, Oldridge DA, Giles JR, Weirick ME, McAllister CM, Awofolaju M, Tanenbaum N, Drapeau EM, Dougherty J, Long S, D'Andrea K, Hamilton JT, McLaughlin M, Williams JC, Adamski S, Kuthuru O; UPenn COVID Processing Unit‡; Frank I, Betts MR, Vella LA, Grifoni A, Weiskopf D, Sette A, Hensley SE, Davenport MP, Bates P, Luning Prak ET, Greenplate AR, Wherry EJ. Goel RR, et al. Among authors: apostolidis sa. Science. 2021 Dec 3;374(6572):abm0829. doi: 10.1126/science.abm0829. Epub 2021 Dec 3. Science. 2021. PMID: 34648302 Free PMC article.
Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions.
Mathew D, Giles JR, Baxter AE, Greenplate AR, Wu JE, Alanio C, Oldridge DA, Kuri-Cervantes L, Pampena MB, D'Andrea K, Manne S, Chen Z, Huang YJ, Reilly JP, Weisman AR, Ittner CAG, Kuthuru O, Dougherty J, Nzingha K, Han N, Kim J, Pattekar A, Goodwin EC, Anderson EM, Weirick ME, Gouma S, Arevalo CP, Bolton MJ, Chen F, Lacey SF, Hensley SE, Apostolidis S, Huang AC, Vella LA; UPenn COVID Processing Unit; Betts MR, Meyer NJ, Wherry EJ. Mathew D, et al. bioRxiv [Preprint]. 2020 May 23:2020.05.20.106401. doi: 10.1101/2020.05.20.106401. bioRxiv. 2020. Update in: Science. 2020 Sep 4;369(6508):eabc8511. doi: 10.1126/science.abc8511 PMID: 32511371 Free PMC article. Updated. Preprint.
Immunologic perturbations in severe COVID-19/SARS-CoV-2 infection.
Kuri-Cervantes L, Pampena MB, Meng W, Rosenfeld AM, Ittner CAG, Weisman AR, Agyekum R, Mathew D, Baxter AE, Vella L, Kuthuru O, Apostolidis S, Bershaw L, Dougherty J, Greenplate AR, Pattekar A, Kim J, Han N, Gouma S, Weirick ME, Arevalo CP, Bolton MJ, Goodwin EC, Anderson EM, Hensley SE, Jones TK, Mangalmurti NS, Luning Prak ET, Wherry EJ, Meyer NJ, Betts MR. Kuri-Cervantes L, et al. bioRxiv [Preprint]. 2020 May 18:2020.05.18.101717. doi: 10.1101/2020.05.18.101717. bioRxiv. 2020. PMID: 32511394 Free PMC article. Preprint.
Comprehensive mapping of immune perturbations associated with severe COVID-19.
Kuri-Cervantes L, Pampena MB, Meng W, Rosenfeld AM, Ittner CAG, Weisman AR, Agyekum RS, Mathew D, Baxter AE, Vella LA, Kuthuru O, Apostolidis SA, Bershaw L, Dougherty J, Greenplate AR, Pattekar A, Kim J, Han N, Gouma S, Weirick ME, Arevalo CP, Bolton MJ, Goodwin EC, Anderson EM, Hensley SE, Jones TK, Mangalmurti NS, Luning Prak ET, Wherry EJ, Meyer NJ, Betts MR. Kuri-Cervantes L, et al. Among authors: apostolidis sa. Sci Immunol. 2020 Jul 15;5(49):eabd7114. doi: 10.1126/sciimmunol.abd7114. Sci Immunol. 2020. PMID: 32669287 Free PMC article.
Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications.
Mathew D, Giles JR, Baxter AE, Oldridge DA, Greenplate AR, Wu JE, Alanio C, Kuri-Cervantes L, Pampena MB, D'Andrea K, Manne S, Chen Z, Huang YJ, Reilly JP, Weisman AR, Ittner CAG, Kuthuru O, Dougherty J, Nzingha K, Han N, Kim J, Pattekar A, Goodwin EC, Anderson EM, Weirick ME, Gouma S, Arevalo CP, Bolton MJ, Chen F, Lacey SF, Ramage H, Cherry S, Hensley SE, Apostolidis SA, Huang AC, Vella LA; UPenn COVID Processing Unit; Betts MR, Meyer NJ, Wherry EJ. Mathew D, et al. Among authors: apostolidis sa. Science. 2020 Sep 4;369(6508):eabc8511. doi: 10.1126/science.abc8511. Epub 2020 Jul 15. Science. 2020. PMID: 32669297 Free PMC article.
Deep Immune Profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19.
Vella L, Giles JR, Baxter AE, Oldridge DA, Diorio C, Kuri-Cervantes L, Alanio C, Pampena MB, Wu JE, Chen Z, Huang YJ, Anderson EM, Gouma S, McNerney KO, Chase J, Burudpakdee C, Lee JH, Apostolidis SA, Huang AC, Mathew D, Kuthuru O, Goodwin EC, Weirick ME, Bolton MJ, Arevalo CP, Ramos A, Jasen C, Giannini HM, DAndrea K, Meyer NJ, Behrens EM, Bassiri H, Hensley SE, Henrickson SE, Teachey DT, Betts MR, Wherry EJ. Vella L, et al. Among authors: apostolidis sa. medRxiv [Preprint]. 2020 Oct 6:2020.09.25.20201863. doi: 10.1101/2020.09.25.20201863. medRxiv. 2020. Update in: Sci Immunol. 2021 Mar 2;6(57):eabf7570. doi: 10.1126/sciimmunol.abf7570 PMID: 32995826 Free PMC article. Updated. Preprint.
Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection.
Anderson EM, Goodwin EC, Verma A, Arevalo CP, Bolton MJ, Weirick ME, Gouma S, McAllister CM, Christensen SR, Weaver J, Hicks P, Manzoni TB, Oniyide O, Ramage H, Mathew D, Baxter AE, Oldridge DA, Greenplate AR, Wu JE, Alanio C, D'Andrea K, Kuthuru O, Dougherty J, Pattekar A, Kim J, Han N, Apostolidis SA, Huang AC, Vella LA; UPenn COVID Processing Unit; Wherry EJ, Meyer NJ, Cherry S, Bates P, Rader DJ, Hensley SE. Anderson EM, et al. Among authors: apostolidis sa. medRxiv [Preprint]. 2020 Nov 10:2020.11.06.20227215. doi: 10.1101/2020.11.06.20227215. medRxiv. 2020. Update in: Cell. 2021 Apr 1;184(7):1858-1864.e10. doi: 10.1016/j.cell.2021.02.010 PMID: 33200143 Free PMC article. Updated. Preprint.
Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection.
Anderson EM, Goodwin EC, Verma A, Arevalo CP, Bolton MJ, Weirick ME, Gouma S, McAllister CM, Christensen SR, Weaver J, Hicks P, Manzoni TB, Oniyide O, Ramage H, Mathew D, Baxter AE, Oldridge DA, Greenplate AR, Wu JE, Alanio C, D'Andrea K, Kuthuru O, Dougherty J, Pattekar A, Kim J, Han N, Apostolidis SA, Huang AC, Vella LA, Kuri-Cervantes L, Pampena MB; UPenn COVID Processing Unit; Betts MR, Wherry EJ, Meyer NJ, Cherry S, Bates P, Rader DJ, Hensley SE. Anderson EM, et al. Among authors: apostolidis sa. Cell. 2021 Apr 1;184(7):1858-1864.e10. doi: 10.1016/j.cell.2021.02.010. Epub 2021 Feb 9. Cell. 2021. PMID: 33631096 Free PMC article.
Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19.
Vella LA, Giles JR, Baxter AE, Oldridge DA, Diorio C, Kuri-Cervantes L, Alanio C, Pampena MB, Wu JE, Chen Z, Huang YJ, Anderson EM, Gouma S, McNerney KO, Chase J, Burudpakdee C, Lee JH, Apostolidis SA, Huang AC, Mathew D, Kuthuru O, Goodwin EC, Weirick ME, Bolton MJ, Arevalo CP, Ramos A, Jasen CJ, Conrey PE, Sayed S, Giannini HM, D'Andrea K; UPenn COVID Processing Unit; Meyer NJ, Behrens EM, Bassiri H, Hensley SE, Henrickson SE, Teachey DT, Betts MR, Wherry EJ. Vella LA, et al. Among authors: apostolidis sa. Sci Immunol. 2021 Mar 2;6(57):eabf7570. doi: 10.1126/sciimmunol.abf7570. Sci Immunol. 2021. PMID: 33653907 Free PMC article.
Longitudinal Analysis Reveals Distinct Antibody and Memory B Cell Responses in SARS-CoV2 Naïve and Recovered Individuals Following mRNA Vaccination.
Goel RR, Apostolidis SA, Painter MM, Mathew D, Pattekar A, Kuthuru O, Gouma S, Kuri-Cervantes L, Meng W, Adamski S, Baxter AE, Giles JR, Weirick ME, McAllister CM, Hicks A, Korte S, Dougherty J, Long S, D'Andrea K, Hamilton JT, Prak ETL, Betts MR, Bates P, Hensley SE, Greenplate AR, Wherry EJ. Goel RR, et al. Among authors: apostolidis sa. medRxiv [Preprint]. 2021 Mar 6:2021.03.03.21252872. doi: 10.1101/2021.03.03.21252872. medRxiv. 2021. Update in: Sci Immunol. 2021 Apr 15;6(58):eabi6950. doi: 10.1126/sciimmunol.abi6950 PMID: 33688691 Free PMC article. Updated. Preprint.
46 results