Tang CL - Search Results

1

Small molecule compound M12 reduces vascular permeability in obese mice via blocking endothelial TRPV4-Nox2 interaction.

Gao MR, Zhang P, Han J, Tang CL, Zhu YF, Kan H, Li HJ, Han XP, Ma X. Gao MR, et al. Among authors: tang cl. Acta Pharmacol Sin. 2022 Jun;43(6):1430-1440. doi: 10.1038/s41401-021-00780-8. Epub 2021 Oct 15. Acta Pharmacol Sin. 2022. PMID: 34654876 Free PMC article.

2

Translocation of PKG1α acts on TRPV4-C1 heteromeric channels to inhibit endothelial Ca(2+) entry.

Zhang P, Mao AQ, Sun CY, Zhang XD, Pan QX, Yang DT, Jin J, Tang CL, Yang ZY, Yao XQ, Lu XJ, Ma X. Zhang P, et al. Among authors: tang cl. Acta Pharmacol Sin. 2016 Sep;37(9):1199-207. doi: 10.1038/aps.2016.43. Epub 2016 Jul 11. Acta Pharmacol Sin. 2016. PMID: 27397542 Free PMC article.

3

Chemotherapy enhances tumor vascularization via Notch signaling-mediated formation of tumor-derived endothelium in breast cancer.

Zhang P, He D, Chen Z, Pan Q, Du F, Zang X, Wang Y, Tang C, Li H, Lu H, Yao X, Jin J, Ma X. Zhang P, et al. Biochem Pharmacol. 2016 Oct 15;118:18-30. doi: 10.1016/j.bcp.2016.08.008. Epub 2016 Aug 9. Biochem Pharmacol. 2016. PMID: 27520484

4

TrpC5 regulates differentiation through the Ca2+/Wnt5a signalling pathway in colorectal cancer.

Chen Z, Tang C, Zhu Y, Xie M, He D, Pan Q, Zhang P, Hua D, Wang T, Jin L, Qi X, Zhu Y, Yao X, Jin J, Ma X. Chen Z, et al. Clin Sci (Lond). 2017 Feb 1;131(3):227-237. doi: 10.1042/CS20160759. Epub 2016 Nov 28. Clin Sci (Lond). 2017. PMID: 27895148

5

Treatment of hypertension by increasing impaired endothelial TRPV4-KCa2.3 interaction.

He D, Pan Q, Chen Z, Sun C, Zhang P, Mao A, Zhu Y, Li H, Lu C, Xie M, Zhou Y, Shen D, Tang C, Yang Z, Jin J, Yao X, Nilius B, Ma X. He D, et al. EMBO Mol Med. 2017 Nov;9(11):1491-1503. doi: 10.15252/emmm.201707725. EMBO Mol Med. 2017. PMID: 28899928 Free PMC article.

6

TRPV4 (Transient Receptor Potential Vanilloid 4) Mediates Endothelium-Dependent Contractions in the Aortas of Hypertensive Mice.

Zhang P, Sun C, Li H, Tang C, Kan H, Yang Z, Mao A, Ma X. Zhang P, et al. Hypertension. 2018 Jan;71(1):134-142. doi: 10.1161/HYPERTENSIONAHA.117.09767. Epub 2017 Nov 6. Hypertension. 2018. PMID: 29109190

7

Curcumin Induces Endothelium-Dependent Relaxation by Activating Endothelial TRPV4 Channels.

Shao J, Han J, Zhu Y, Mao A, Wang Z, Zhang K, Zhang X, Zhang Y, Tang C, Ma X. Shao J, et al. J Cardiovasc Transl Res. 2019 Dec;12(6):600-607. doi: 10.1007/s12265-019-09928-8. Epub 2019 Oct 29. J Cardiovasc Transl Res. 2019. PMID: 31664615

8

Blocking endothelial TRPV4-Nox2 interaction helps reduce ROS production and inflammation, and improves vascular function in obese mice.

Gao M, Han J, Zhu Y, Tang C, Liu L, Xiao W, Ma X. Gao M, et al. J Mol Cell Cardiol. 2021 Aug;157:66-76. doi: 10.1016/j.yjmcc.2021.04.008. Epub 2021 Apr 28. J Mol Cell Cardiol. 2021. PMID: 33932464

9

Endothelial TRPV4-eNOS coupling as a vital therapy target for treatment of hypertension.

Mao A, Zhang P, Zhang K, Kan H, He D, Han X, Wang Z, Tang C, Ma X. Mao A, et al. Br J Pharmacol. 2022 May;179(10):2297-2312. doi: 10.1111/bph.15755. Epub 2022 Jan 28. Br J Pharmacol. 2022. PMID: 34822720 Free article.

10

Functional role of coupling the endothelial TRPV4 and K_Ca 3.1 channels in regulating coronary vascular tone.

Mao A, He D, Zhang K, Gao M, Kan H, Wang Z, Tang C, Ma X. Mao A, et al. Br J Pharmacol. 2023 Sep;180(17):2266-2279. doi: 10.1111/bph.16082. Epub 2023 May 6. Br J Pharmacol. 2023. PMID: 37005734 Free article.

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