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Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3.
Chandrasekaran A, Dittlau KS, Corsi GI, Haukedal H, Doncheva NT, Ramakrishna S, Ambardar S, Salcedo C, Schmidt SI, Zhang Y, Cirera S, Pihl M, Schmid B, Nielsen TT, Nielsen JE, Kolko M, Kobolák J, Dinnyés A, Hyttel P, Palakodeti D, Gorodkin J, Muddashetty RS, Meyer M, Aldana BI, Freude KK. Chandrasekaran A, et al. Among authors: schmidt si. Stem Cell Reports. 2021 Nov 9;16(11):2736-2751. doi: 10.1016/j.stemcr.2021.09.013. Epub 2021 Oct 21. Stem Cell Reports. 2021. PMID: 34678206 Free PMC article.
PARK2 Mutation Causes Metabolic Disturbances and Impaired Survival of Human iPSC-Derived Neurons.
Bogetofte H, Jensen P, Ryding M, Schmidt SI, Okarmus J, Ritter L, Worm CS, Hohnholt MC, Azevedo C, Roybon L, Bak LK, Waagepetersen H, Ryan BJ, Wade-Martins R, Larsen MR, Meyer M. Bogetofte H, et al. Among authors: schmidt si. Front Cell Neurosci. 2019 Jul 5;13:297. doi: 10.3389/fncel.2019.00297. eCollection 2019. Front Cell Neurosci. 2019. PMID: 31333417 Free PMC article.
Perturbations in RhoA signalling cause altered migration and impaired neuritogenesis in human iPSC-derived neural cells with PARK2 mutation.
Bogetofte H, Jensen P, Okarmus J, Schmidt SI, Agger M, Ryding M, Nørregaard P, Fenger C, Zeng X, Graakjær J, Ryan BJ, Wade-Martins R, Larsen MR, Meyer M. Bogetofte H, et al. Among authors: schmidt si. Neurobiol Dis. 2019 Dec;132:104581. doi: 10.1016/j.nbd.2019.104581. Epub 2019 Aug 21. Neurobiol Dis. 2019. PMID: 31445161 Free article.
Microglia-Secreted Factors Enhance Dopaminergic Differentiation of Tissue- and iPSC-Derived Human Neural Stem Cells.
Schmidt SI, Bogetofte H, Ritter L, Agergaard JB, Hammerich D, Kabiljagic AA, Wlodarczyk A, Lopez SG, Sørensen MD, Jørgensen ML, Okarmus J, Serrano AM, Kristensen BW, Freude K, Owens T, Meyer M. Schmidt SI, et al. Stem Cell Reports. 2021 Feb 9;16(2):281-294. doi: 10.1016/j.stemcr.2020.12.011. Epub 2021 Jan 21. Stem Cell Reports. 2021. PMID: 33482100 Free PMC article.
Identification of bioactive metabolites in human iPSC-derived dopaminergic neurons with PARK2 mutation: Altered mitochondrial and energy metabolism.
Okarmus J, Havelund JF, Ryding M, Schmidt SI, Bogetofte H, Heon-Roberts R, Wade-Martins R, Cowley SA, Ryan BJ, Færgeman NJ, Hyttel P, Meyer M. Okarmus J, et al. Among authors: schmidt si. Stem Cell Reports. 2021 Jun 8;16(6):1510-1526. doi: 10.1016/j.stemcr.2021.04.022. Epub 2021 May 27. Stem Cell Reports. 2021. PMID: 34048689 Free PMC article.
43 results