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Shiga Toxins as Antitumor Tools.
Robert A, Wiels J. Robert A, et al. Among authors: wiels j. Toxins (Basel). 2021 Sep 28;13(10):690. doi: 10.3390/toxins13100690. Toxins (Basel). 2021. PMID: 34678982 Free PMC article. Review.
Constitutive autophagy contributes to resistance to TP53-mediated apoptosis in Epstein-Barr virus-positive latency III B-cell lymphoproliferations.
Pujals A, Favre L, Pioche-Durieu C, Robert A, Meurice G, Le Gentil M, Chelouah S, Martin-Garcia N, Le Cam E, Guettier C, Raphaël M, Vassilev LT, Gaulard P, Codogno P, Lipinski M, Wiels J. Pujals A, et al. Among authors: wiels j. Autophagy. 2015;11(12):2275-87. doi: 10.1080/15548627.2015.1115939. Autophagy. 2015. PMID: 26565591 Free PMC article.
Drimane Derivatives as the First Examples of Covalent BH3 Mimetics that Target MCL-1.
Daressy F, Malard F, Seguy L, Guérineau V, Apel C, Dumontet V, Robert A, Groo AC, Litaudon M, Bignon J, Desrat S, Malzert-Fréon A, Wiels J, Lescop E, Roussi F. Daressy F, et al. Among authors: wiels j. ChemMedChem. 2021 Jun 7;16(11):1788-1797. doi: 10.1002/cmdc.202100011. Epub 2021 Mar 23. ChemMedChem. 2021. PMID: 33665938
NA1-115-7, from Zygogynum pancheri, is a new selective MCL-1 inhibitor inducing the apoptosis of hematological cancer cells but non-toxic to normal blood cells or cardiomyocytes.
Daressy F, Séguy L, Favre L, Corvaisier S, Apel C, Groo AC, Litaudon M, Dumontet V, Malzert-Fréon A, Desrat S, Roussi F, Robert A, Wiels J. Daressy F, et al. Among authors: wiels j. Biomed Pharmacother. 2022 Oct;154:113546. doi: 10.1016/j.biopha.2022.113546. Epub 2022 Aug 18. Biomed Pharmacother. 2022. PMID: 35988426 Free article.
Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma.
Harrington CT, Sotillo E, Robert A, Hayer KE, Bogusz AM, Psathas J, Yu D, Taylor D, Dang CV, Klein PS, Hogarty MD, Geoerger B, El-Deiry WS, Wiels J, Thomas-Tikhonenko A. Harrington CT, et al. Among authors: wiels j. Leukemia. 2019 Oct;33(10):2429-2441. doi: 10.1038/s41375-019-0454-4. Epub 2019 Mar 26. Leukemia. 2019. PMID: 30914792 Free PMC article.
84 results