Mast N - Search Results

1

Characterizations of Hamster Retina as a Model for Studies of Retinal Cholesterol Homeostasis.

El-Darzi N, Mast N, Dailey B, Denker J, Li Y, Vance J, Pikuleva IA. El-Darzi N, et al. Among authors: mast n. Biology (Basel). 2021 Oct 6;10(10):1003. doi: 10.3390/biology10101003. Biology (Basel). 2021. PMID: 34681102 Free PMC article.

2

Broad substrate specificity of human cytochrome P450 46A1 which initiates cholesterol degradation in the brain.

Mast N, Norcross R, Andersson U, Shou M, Nakayama K, Bjorkhem I, Pikuleva IA. Mast N, et al. Biochemistry. 2003 Dec 9;42(48):14284-92. doi: 10.1021/bi035512f. Biochemistry. 2003. PMID: 14640697

3

Expression of human cytochrome P450 46A1 in Escherichia coli: effects of N- and C-terminal modifications.

Mast N, Andersson U, Nakayama K, Bjorkhem I, Pikuleva IA. Mast N, et al. Arch Biochem Biophys. 2004 Aug 1;428(1):99-108. doi: 10.1016/j.abb.2004.05.012. Arch Biochem Biophys. 2004. PMID: 15234274

4

Cholesterol binding to cytochrome P450 7A1, a key enzyme in bile acid biosynthesis.

Mast N, Graham SE, Andersson U, Bjorkhem I, Hill C, Peterson J, Pikuleva IA. Mast N, et al. Biochemistry. 2005 Mar 8;44(9):3259-71. doi: 10.1021/bi047566a. Biochemistry. 2005. PMID: 15736936

5

A simple and rapid method to measure cholesterol binding to P450s and other proteins.

Mast N, Pikuleva IA. Mast N, et al. J Lipid Res. 2005 Jul;46(7):1561-8. doi: 10.1194/jlr.D500008-JLR200. Epub 2005 Apr 16. J Lipid Res. 2005. PMID: 15834119 Free article.

6

Distinct binding of cholesterol and 5beta-cholestane-3alpha,7alpha,12alpha-triol to cytochrome P450 27A1: evidence from modeling and site-directed mutagenesis studies.

Mast N, Murtazina D, Liu H, Graham SE, Bjorkhem I, Halpert JR, Peterson J, Pikuleva IA. Mast N, et al. Biochemistry. 2006 Apr 11;45(14):4396-404. doi: 10.1021/bi052654w. Biochemistry. 2006. PMID: 16584175

7

Use of complementary cation and anion heavy-atom salt derivatives to solve the structure of cytochrome P450 46A1.

White MA, Mast N, Bjorkhem I, Johnson EF, Stout CD, Pikuleva IA. White MA, et al. Among authors: mast n. Acta Crystallogr D Biol Crystallogr. 2008 May;64(Pt 5):487-95. doi: 10.1107/S0907444908004046. Epub 2008 Apr 19. Acta Crystallogr D Biol Crystallogr. 2008. PMID: 18453684 Free PMC article.

8

Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain.

Mast N, White MA, Bjorkhem I, Johnson EF, Stout CD, Pikuleva IA. Mast N, et al. Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9546-51. doi: 10.1073/pnas.0803717105. Epub 2008 Jul 9. Proc Natl Acad Sci U S A. 2008. PMID: 18621681 Free PMC article.

9

Studies of membrane topology of mitochondrial cholesterol hydroxylases CYPs 27A1 and 11A1.

Pikuleva IA, Mast N, Liao WL, Turko IV. Pikuleva IA, et al. Among authors: mast n. Lipids. 2008 Dec;43(12):1127-32. doi: 10.1007/s11745-008-3234-x. Epub 2008 Sep 13. Lipids. 2008. PMID: 18791760 Free PMC article.

10

Combined use of mass spectrometry and heterologous expression for identification of membrane-interacting peptides in cytochrome P450 46A1 and NADPH-cytochrome P450 oxidoreductase.

Mast N, Liao WL, Pikuleva IA, Turko IV. Mast N, et al. Arch Biochem Biophys. 2009 Mar 1;483(1):81-9. doi: 10.1016/j.abb.2009.01.002. Epub 2009 Jan 10. Arch Biochem Biophys. 2009. PMID: 19161969 Free PMC article.

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