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Novel indolin-2-one-based sulfonamides as carbonic anhydrase inhibitors: Synthesis, in vitro biological evaluation against carbonic anhydrases isoforms I, II, IV and VII and molecular docking studies.
Eldehna WM, Al-Ansary GH, Bua S, Nocentini A, Gratteri P, Altoukhy A, Ghabbour H, Ahmed HY, Supuran CT. Eldehna WM, et al. Among authors: nocentini a. Eur J Med Chem. 2017 Feb 15;127:521-530. doi: 10.1016/j.ejmech.2017.01.017. Epub 2017 Jan 11. Eur J Med Chem. 2017. PMID: 28109946
Synthesis of bulky-tailed sulfonamides incorporating pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-1(5H)-yl) moieties and evaluation of their carbonic anhydrases I, II, IV and IX inhibitory effects.
Fares M, Eladwy RA, Nocentini A, El Hadi SRA, Ghabbour HA, Abdel-Megeed A, Eldehna WM, Abdel-Aziz HA, Supuran CT. Fares M, et al. Among authors: nocentini a. Bioorg Med Chem. 2017 Apr 1;25(7):2210-2217. doi: 10.1016/j.bmc.2017.02.037. Epub 2017 Feb 21. Bioorg Med Chem. 2017. PMID: 28256371
300 results