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Activation of Notch and Myc Signaling via B-cell-Restricted Depletion of Dnmt3a Generates a Consistent Murine Model of Chronic Lymphocytic Leukemia.
Biran A, Yin S, Kretzmer H, Ten Hacken E, Parvin S, Lucas F, Uduman M, Gutierrez C, Dangle N, Billington L, Regis FF, Rassenti LZ, Mohammad A, Hoffmann GB, Stevenson K, Zheng M, Witten E, Fernandes SM, Tausch E, Sun C, Stilgenbauer S, Brown JR, Kipps TJ, Aster JC, Gnirke A, Neuberg DS, Letai A, Wang L, Carrasco RD, Meissner A, Wu CJ. Biran A, et al. Among authors: mohammad a. Cancer Res. 2021 Dec 15;81(24):6117-6130. doi: 10.1158/0008-5472.CAN-21-1273. Epub 2021 Oct 22. Cancer Res. 2021. PMID: 34686499 Free PMC article.
Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells.
Choi J, Huebner AJ, Clement K, Walsh RM, Savol A, Lin K, Gu H, Di Stefano B, Brumbaugh J, Kim SY, Sharif J, Rose CM, Mohammad A, Odajima J, Charron J, Shioda T, Gnirke A, Gygi S, Koseki H, Sadreyev RI, Xiao A, Meissner A, Hochedlinger K. Choi J, et al. Among authors: mohammad a. Nature. 2017 Aug 10;548(7666):219-223. doi: 10.1038/nature23274. Epub 2017 Jul 26. Nature. 2017. PMID: 28746311 Free PMC article.
Genome-wide tracking of dCas9-methyltransferase footprints.
Galonska C, Charlton J, Mattei AL, Donaghey J, Clement K, Gu H, Mohammad AW, Stamenova EK, Cacchiarelli D, Klages S, Timmermann B, Cantz T, Schöler HR, Gnirke A, Ziller MJ, Meissner A. Galonska C, et al. Among authors: mohammad aw. Nat Commun. 2018 Feb 9;9(1):597. doi: 10.1038/s41467-017-02708-5. Nat Commun. 2018. PMID: 29426832 Free PMC article.
Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade.
Shukla SA, Bachireddy P, Schilling B, Galonska C, Zhan Q, Bango C, Langer R, Lee PC, Gusenleitner D, Keskin DB, Babadi M, Mohammad A, Gnirke A, Clement K, Cartun ZJ, Van Allen EM, Miao D, Huang Y, Snyder A, Merghoub T, Wolchok JD, Garraway LA, Meissner A, Weber JS, Hacohen N, Neuberg D, Potts PR, Murphy GF, Lian CG, Schadendorf D, Hodi FS, Wu CJ. Shukla SA, et al. Among authors: mohammad a. Cell. 2018 Apr 19;173(3):624-633.e8. doi: 10.1016/j.cell.2018.03.026. Epub 2018 Apr 12. Cell. 2018. PMID: 29656892 Free PMC article.
Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to the graft-versus-leukemia effect.
Bachireddy P, Ennis C, Nguyen VN, Gohil SH, Clement K, Shukla SA, Forman J, Barkas N, Freeman S, Bavli N, Elagina L, Leshchiner I, Mohammad AW, Mathewson ND, Keskin DB, Rassenti LZ, Kipps TJ, Brown JR, Getz G, Ho VT, Gnirke A, Neuberg D, Soiffer RJ, Ritz J, Alyea EP, Kharchenko PV, Wu CJ. Bachireddy P, et al. Among authors: mohammad aw. Sci Transl Med. 2020 Sep 16;12(561):eabb7661. doi: 10.1126/scitranslmed.abb7661. Sci Transl Med. 2020. PMID: 32938797 Free PMC article.
Preneoplastic Alterations Define CLL DNA Methylome and Persist through Disease Progression and Therapy.
Kretzmer H, Biran A, Purroy N, Lemvigh CK, Clement K, Gruber M, Gu H, Rassenti L, Mohammad AW, Lesnick C, Slager SL, Braggio E, Shanafelt TD, Kay NE, Fernandes SM, Brown JR, Wang L, Li S, Livak KJ, Neuberg DS, Klages S, Timmermann B, Kipps TJ, Campo E, Gnirke A, Wu CJ, Meissner A. Kretzmer H, et al. Among authors: mohammad aw. Blood Cancer Discov. 2021 Jan;2(1):54-69. doi: 10.1158/2643-3230.BCD-19-0058. Epub 2020 Dec 3. Blood Cancer Discov. 2021. PMID: 33604581 Free PMC article.
Smart-RRBS for single-cell methylome and transcriptome analysis.
Gu H, Raman AT, Wang X, Gaiti F, Chaligne R, Mohammad AW, Arczewska A, Smith ZD, Landau DA, Aryee MJ, Meissner A, Gnirke A. Gu H, et al. Among authors: mohammad aw. Nat Protoc. 2021 Aug;16(8):4004-4030. doi: 10.1038/s41596-021-00571-9. Epub 2021 Jul 9. Nat Protoc. 2021. PMID: 34244697 Free PMC article. Review.
Comparative genomics of the closely related fungal genera Cryptococcus and Kwoniella reveals karyotype dynamics and suggests evolutionary mechanisms of pathogenesis.
Coelho MA, David-Palma M, Shea T, Bowers K, McGinley-Smith S, Mohammad AW, Gnirke A, Yurkov AM, Nowrousian M, Sun S, Cuomo CA, Heitman J. Coelho MA, et al. Among authors: mohammad aw. PLoS Biol. 2024 Jun 6;22(6):e3002682. doi: 10.1371/journal.pbio.3002682. eCollection 2024 Jun. PLoS Biol. 2024. PMID: 38843310 Free PMC article.
Comparative genomics of Cryptococcus and Kwoniella reveals pathogenesis evolution and contrasting karyotype dynamics via intercentromeric recombination or chromosome fusion.
Coelho MA, David-Palma M, Shea T, Bowers K, McGinley-Smith S, Mohammad AW, Gnirke A, Yurkov AM, Nowrousian M, Sun S, Cuomo CA, Heitman J. Coelho MA, et al. Among authors: mohammad aw. bioRxiv [Preprint]. 2024 Jan 13:2023.12.27.573464. doi: 10.1101/2023.12.27.573464. bioRxiv. 2024. Update in: PLoS Biol. 2024 Jun 6;22(6):e3002682. doi: 10.1371/journal.pbio.3002682 PMID: 38234769 Free PMC article. Updated. Preprint.
Effect of exogenous β-hydroxybutyrate on BDNF signalling, cognition, and amyloid precursor protein processing in humans with T2D and insulin resistant rodents.
Baranowski BJ, Oliveira BF, Falkenhain K, Little JP, Mohammad A, Beaudette S, Finch MS, Caldwell HG, Neudorf H, MacPherson REK, Walsh JJ. Baranowski BJ, et al. Among authors: mohammad a. Am J Physiol Cell Physiol. 2025 Jan 13. doi: 10.1152/ajpcell.00867.2024. Online ahead of print. Am J Physiol Cell Physiol. 2025. PMID: 39804761
1,315 results