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83 results

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Safety and efficacy of losartan for the reduction of brain atrophy in clinically diagnosed Alzheimer's disease (the RADAR trial): a double-blind, randomised, placebo-controlled, phase 2 trial.
Kehoe PG, Turner N, Howden B, Jarutyte L, Clegg SL, Malone IB, Barnes J, Nielsen C, Sudre CH, Wilson A, Thai NJ, Blair PS, Coulthard E, Lane JA, Passmore P, Taylor J, Mutsaerts HJ, Thomas DL, Fox NC, Wilkinson I, Ben-Shlomo Y; RADAR investigators. Kehoe PG, et al. Among authors: malone ib. Lancet Neurol. 2021 Nov;20(11):895-906. doi: 10.1016/S1474-4422(21)00263-5. Lancet Neurol. 2021. PMID: 34687634 Free PMC article. Clinical Trial.
Potential endpoints for clinical trials in premanifest and early Huntington's disease in the TRACK-HD study: analysis of 24 month observational data.
Tabrizi SJ, Reilmann R, Roos RA, Durr A, Leavitt B, Owen G, Jones R, Johnson H, Craufurd D, Hicks SL, Kennard C, Landwehrmeyer B, Stout JC, Borowsky B, Scahill RI, Frost C, Langbehn DR; TRACK-HD investigators. Tabrizi SJ, et al. Lancet Neurol. 2012 Jan;11(1):42-53. doi: 10.1016/S1474-4422(11)70263-0. Epub 2011 Dec 2. Lancet Neurol. 2012. PMID: 22137354
Vascular and Alzheimer's disease markers independently predict brain atrophy rate in Alzheimer's Disease Neuroimaging Initiative controls.
Barnes J, Carmichael OT, Leung KK, Schwarz C, Ridgway GR, Bartlett JW, Malone IB, Schott JM, Rossor MN, Biessels GJ, DeCarli C, Fox NC; Alzheimer's Disease Neuroimaging Initiative. Barnes J, et al. Among authors: malone ib. Neurobiol Aging. 2013 Aug;34(8):1996-2002. doi: 10.1016/j.neurobiolaging.2013.02.003. Epub 2013 Mar 21. Neurobiol Aging. 2013. PMID: 23522844 Free PMC article.
Magnetic resonance imaging evidence for presymptomatic change in thalamus and caudate in familial Alzheimer's disease.
Ryan NS, Keihaninejad S, Shakespeare TJ, Lehmann M, Crutch SJ, Malone IB, Thornton JS, Mancini L, Hyare H, Yousry T, Ridgway GR, Zhang H, Modat M, Alexander DC, Rossor MN, Ourselin S, Fox NC. Ryan NS, et al. Among authors: malone ib. Brain. 2013 May;136(Pt 5):1399-414. doi: 10.1093/brain/awt065. Epub 2013 Mar 28. Brain. 2013. PMID: 23539189 Free PMC article.
Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study: analysis of 36-month observational data.
Tabrizi SJ, Scahill RI, Owen G, Durr A, Leavitt BR, Roos RA, Borowsky B, Landwehrmeyer B, Frost C, Johnson H, Craufurd D, Reilmann R, Stout JC, Langbehn DR; TRACK-HD Investigators. Tabrizi SJ, et al. Lancet Neurol. 2013 Jul;12(7):637-49. doi: 10.1016/S1474-4422(13)70088-7. Epub 2013 May 9. Lancet Neurol. 2013. PMID: 23664844
The pattern of atrophy in familial Alzheimer disease: volumetric MRI results from the DIAN study.
Cash DM, Ridgway GR, Liang Y, Ryan NS, Kinnunen KM, Yeatman T, Malone IB, Benzinger TL, Jack CR Jr, Thompson PM, Ghetti BF, Saykin AJ, Masters CL, Ringman JM, Salloway SP, Schofield PR, Sperling RA, Cairns NJ, Marcus DS, Xiong C, Bateman RJ, Morris JC, Rossor MN, Ourselin S, Fox NC; Dominantly Inherited Alzheimer Network (DIAN). Cash DM, et al. Among authors: malone ib. Neurology. 2013 Oct 15;81(16):1425-33. doi: 10.1212/WNL.0b013e3182a841c6. Epub 2013 Sep 18. Neurology. 2013. PMID: 24049139 Free PMC article.
83 results