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Escalating regulation of 5T4-specific IFN-γ+ CD4+ T cells distinguishes colorectal cancer patients from healthy controls and provides a target for in vivo therapy.
Scurr M, Bloom A, Pembroke T, Srinivasan R, Brown C, Smart K, Bridgeman H, Davies M, Hargest R, Phillips S, Christian A, Hockey T, Gallimore A, Godkin A. Scurr M, et al. Cancer Immunol Res. 2013 Dec;1(6):10.1158/2326-6066.CIR-13-0035. doi: 10.1158/2326-6066.CIR-13-0035. Cancer Immunol Res. 2013. PMID: 24409450 Free PMC article.
Low-Dose Cyclophosphamide Induces Antitumor T-Cell Responses, which Associate with Survival in Metastatic Colorectal Cancer.
Scurr M, Pembroke T, Bloom A, Roberts D, Thomson A, Smart K, Bridgeman H, Adams R, Brewster A, Jones R, Gwynne S, Blount D, Harrop R, Hills R, Gallimore A, Godkin A. Scurr M, et al. Clin Cancer Res. 2017 Nov 15;23(22):6771-6780. doi: 10.1158/1078-0432.CCR-17-0895. Epub 2017 Aug 29. Clin Cancer Res. 2017. PMID: 28855352 Free PMC article. Clinical Trial.
Effect of Modified Vaccinia Ankara-5T4 and Low-Dose Cyclophosphamide on Antitumor Immunity in Metastatic Colorectal Cancer: A Randomized Clinical Trial.
Scurr M, Pembroke T, Bloom A, Roberts D, Thomson A, Smart K, Bridgeman H, Adams R, Brewster A, Jones R, Gwynne S, Blount D, Harrop R, Wright M, Hills R, Gallimore A, Godkin A. Scurr M, et al. JAMA Oncol. 2017 Oct 12;3(10):e172579. doi: 10.1001/jamaoncol.2017.2579. Epub 2017 Oct 12. JAMA Oncol. 2017. PMID: 28880972 Free PMC article. Clinical Trial.
T-cell modulation by cyclophosphamide for tumour therapy.
Hughes E, Scurr M, Campbell E, Jones E, Godkin A, Gallimore A. Hughes E, et al. Immunology. 2018 May;154(1):62-68. doi: 10.1111/imm.12913. Epub 2018 Mar 9. Immunology. 2018. PMID: 29460448 Free PMC article. Review.
24 results