Cummins MC - Search Results

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Designer proteins that competitively inhibit Gα_q by targeting its effector site.

Hussain M, Cummins MC, Endo-Streeter S, Sondek J, Kuhlman B. Hussain M, et al. Among authors: cummins mc. J Biol Chem. 2021 Dec;297(6):101348. doi: 10.1016/j.jbc.2021.101348. Epub 2021 Oct 27. J Biol Chem. 2021. PMID: 34715131 Free PMC article.

Perturbing the energy landscape for improved packing during computational protein design.

Maguire JB, Haddox HK, Strickland D, Halabiya SF, Coventry B, Griffin JR, Pulavarti SVSRK, Cummins M, Thieker DF, Klavins E, Szyperski T, DiMaio F, Baker D, Kuhlman B. Maguire JB, et al. Proteins. 2021 Apr;89(4):436-449. doi: 10.1002/prot.26030. Epub 2020 Dec 11. Proteins. 2021. PMID: 33249652 Free PMC article.

AlphaFold accurately predicts distinct conformations based on the oligomeric state of a de novo designed protein.

Cummins MC, Jacobs TM, Teets FD, DiMaio F, Tripathy A, Kuhlman B. Cummins MC, et al. Protein Sci. 2022 Jul;31(7):e4368. doi: 10.1002/pro.4368. Protein Sci. 2022. PMID: 35762713 Free PMC article.

De novo design of stable proteins that efficaciously inhibit oncogenic G proteins.

Cummins MC, Tripathy A, Sondek J, Kuhlman B. Cummins MC, et al. Protein Sci. 2023 Aug;32(8):e4713. doi: 10.1002/pro.4713. Protein Sci. 2023. PMID: 37368504 Free PMC article.

De novo design of stable proteins that efficaciously inhibit oncogenic G proteins.

Cummins MC, Tripathy A, Sondek J, Kuhlman B. Cummins MC, et al. bioRxiv [Preprint]. 2023 Mar 28:2023.03.28.534629. doi: 10.1101/2023.03.28.534629. bioRxiv. 2023. Update in: Protein Sci. 2023 Aug;32(8):e4713. doi: 10.1002/pro.4713 PMID: 37034763 Free PMC article. Updated. Preprint.

An Adaptation To Life In Acid Through A Novel Mevalonate Pathway.

Vinokur JM, Cummins MC, Korman TP, Bowie JU. Vinokur JM, et al. Among authors: cummins mc. Sci Rep. 2016 Dec 22;6:39737. doi: 10.1038/srep39737. Sci Rep. 2016. PMID: 28004831 Free PMC article.

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