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Hypoxia-induced pulmonary hypertension-Utilizing experiments of nature.
Gassmann M, Cowburn A, Gu H, Li J, Rodriguez M, Babicheva A, Jain PP, Xiong M, Gassmann NN, Yuan JX, Wilkins MR, Zhao L. Gassmann M, et al. Among authors: yuan jx. Br J Pharmacol. 2021 Jan;178(1):121-131. doi: 10.1111/bph.15144. Epub 2020 Aug 28. Br J Pharmacol. 2021. PMID: 32464698 Free article. Review.
Chronic Hypoxia Decreases Endothelial Connexin 40, Attenuates Endothelium-Dependent Hyperpolarization-Mediated Relaxation in Small Distal Pulmonary Arteries, and Leads to Pulmonary Hypertension.
Si R, Zhang Q, Cabrera JTO, Zheng Q, Tsuji-Hosokawa A, Watanabe M, Hosokawa S, Xiong M, Jain PP, Ashton AW, Yuan JX, Wang J, Makino A. Si R, et al. Among authors: yuan jx. J Am Heart Assoc. 2020 Dec 15;9(24):e018327. doi: 10.1161/JAHA.120.018327. Epub 2020 Dec 12. J Am Heart Assoc. 2020. PMID: 33307937 Free PMC article.
Notch Activation of Ca(2+) Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension.
Smith KA, Voiriot G, Tang H, Fraidenburg DR, Song S, Yamamura H, Yamamura A, Guo Q, Wan J, Pohl NM, Tauseef M, Bodmer R, Ocorr K, Thistlethwaite PA, Haddad GG, Powell FL, Makino A, Mehta D, Yuan JX. Smith KA, et al. Among authors: yuan jx. Am J Respir Cell Mol Biol. 2015 Sep;53(3):355-67. doi: 10.1165/rcmb.2014-0235OC. Am J Respir Cell Mol Biol. 2015. PMID: 25569851 Free PMC article.
MDM2-Mediated Ubiquitination of Angiotensin-Converting Enzyme 2 Contributes to the Development of Pulmonary Arterial Hypertension.
Shen H, Zhang J, Wang C, Jain PP, Xiong M, Shi X, Lei Y, Chen S, Yin Q, Thistlethwaite PA, Wang J, Gong K, Yuan ZY, Yuan JX, Shyy JY. Shen H, et al. Among authors: yuan zy, yuan jx. Circulation. 2020 Sep 22;142(12):1190-1204. doi: 10.1161/CIRCULATIONAHA.120.048191. Epub 2020 Jul 28. Circulation. 2020. PMID: 32755395 Free PMC article.
Halofuginone, a promising drug for treatment of pulmonary hypertension.
Jain PP, Zhao T, Xiong M, Song S, Lai N, Zheng Q, Chen J, Carr SG, Babicheva A, Izadi A, Rodriguez M, Rahimi S, Balistrieri F, Rahimi S, Simonson T, Valdez-Jasso D, Thistlethwaite PA, Shyy JY, Wang J, Makino A, Yuan JX. Jain PP, et al. Among authors: yuan jx. Br J Pharmacol. 2021 Sep;178(17):3373-3394. doi: 10.1111/bph.15442. Epub 2021 Jul 31. Br J Pharmacol. 2021. PMID: 33694155 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 35557394
Endothelial platelet-derived growth factor-mediated activation of smooth muscle platelet-derived growth factor receptors in pulmonary arterial hypertension.
Wu K, Tang H, Lin R, Carr SG, Wang Z, Babicheva A, Ayon RJ, Jain PP, Xiong M, Rodriguez M, Rahimi S, Balistrieri F, Rahimi S, Valdez-Jasso D, Simonson TS, Desai AA, Garcia JGN, Shyy JY, Thistlethwaite PA, Wang J, Makino A, Yuan JX. Wu K, et al. Among authors: yuan jx. Pulm Circ. 2020 Sep 10;10(3):2045894020948470. doi: 10.1177/2045894020948470. eCollection 2020 Jul-Sep. Pulm Circ. 2020. PMID: 33294172 Free PMC article.
365 results