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A phase Ib study of GSK3052230, an FGF ligand trap in combination with pemetrexed and cisplatin in patients with malignant pleural mesothelioma.
van Brummelen EMJ, Levchenko E, Dómine M, Fennell DA, Kindler HL, Viteri S, Gadgeel S, López PG, Kostorov V, Morgensztern D, Orlov S, Zauderer MG, Vansteenkiste JF, Baker-Neblett K, Vasquez J, Wang X, Bellovin DI, Schellens JHM, Yan L, Mitrica I, DeYoung MP, Trigo J. van Brummelen EMJ, et al. Among authors: bellovin di. Invest New Drugs. 2020 Apr;38(2):457-467. doi: 10.1007/s10637-019-00783-7. Epub 2019 May 7. Invest New Drugs. 2020. PMID: 31065954 Free PMC article. Clinical Trial.
MYC ASO Impedes Tumorigenesis and Elicits Oncogene Addiction in Autochthonous Transgenic Mouse Models of HCC and RCC.
Dhanasekaran R, Park J, Yevtodiyenko A, Bellovin DI, Adam SJ, Kd AR, Gabay M, Fernando H, Arzeno J, Arjunan V, Gryanzov S, Felsher DW. Dhanasekaran R, et al. Among authors: bellovin di. Mol Ther Nucleic Acids. 2020 Sep 4;21:850-859. doi: 10.1016/j.omtn.2020.07.008. Epub 2020 Jul 10. Mol Ther Nucleic Acids. 2020. PMID: 32805488 Free PMC article.
MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells.
Altman BJ, Hsieh AL, Sengupta A, Krishnanaiah SY, Stine ZE, Walton ZE, Gouw AM, Venkataraman A, Li B, Goraksha-Hicks P, Diskin SJ, Bellovin DI, Simon MC, Rathmell JC, Lazar MA, Maris JM, Felsher DW, Hogenesch JB, Weljie AM, Dang CV. Altman BJ, et al. Among authors: bellovin di. Cell Metab. 2015 Dec 1;22(6):1009-19. doi: 10.1016/j.cmet.2015.09.003. Epub 2015 Sep 17. Cell Metab. 2015. PMID: 26387865 Free PMC article.
MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism.
Shroff EH, Eberlin LS, Dang VM, Gouw AM, Gabay M, Adam SJ, Bellovin DI, Tran PT, Philbrick WM, Garcia-Ocana A, Casey SC, Li Y, Dang CV, Zare RN, Felsher DW. Shroff EH, et al. Among authors: bellovin di. Proc Natl Acad Sci U S A. 2015 May 26;112(21):6539-44. doi: 10.1073/pnas.1507228112. Epub 2015 May 11. Proc Natl Acad Sci U S A. 2015. PMID: 25964345 Free PMC article.
19 results