Sontheimer EJ - Search Results

1

Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo.

Ibraheim R, Tai PWL, Mir A, Javeed N, Wang J, Rodríguez TC, Namkung S, Nelson S, Khokhar ES, Mintzer E, Maitland S, Chen Z, Cao Y, Tsagkaraki E, Wolfe SA, Wang D, Pai AA, Xue W, Gao G, Sontheimer EJ. Ibraheim R, et al. Among authors: sontheimer ej. Nat Commun. 2021 Nov 1;12(1):6267. doi: 10.1038/s41467-021-26518-y. Nat Commun. 2021. PMID: 34725353 Free PMC article.

2

Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses.

Wang D, Mou H, Li S, Li Y, Hough S, Tran K, Li J, Yin H, Anderson DG, Sontheimer EJ, Weng Z, Gao G, Xue W. Wang D, et al. Among authors: sontheimer ej. Hum Gene Ther. 2015 Jul;26(7):432-42. doi: 10.1089/hum.2015.087. Hum Gene Ther. 2015. PMID: 26086867 Free PMC article.

3

Cas9 gets a classmate.

Sontheimer EJ, Wolfe SA. Sontheimer EJ, et al. Nat Biotechnol. 2015 Dec 9;33(12):1240-1241. doi: 10.1038/nbt.3426. Nat Biotechnol. 2015. PMID: 26650011 No abstract available.

4

CRISPR/Cas9-mediated genome editing induces exon skipping by alternative splicing or exon deletion.

Mou H, Smith JL, Peng L, Yin H, Moore J, Zhang XO, Song CQ, Sheel A, Wu Q, Ozata DM, Li Y, Anderson DG, Emerson CP, Sontheimer EJ, Moore MJ, Weng Z, Xue W. Mou H, et al. Among authors: sontheimer ej. Genome Biol. 2017 Jun 14;18(1):108. doi: 10.1186/s13059-017-1237-8. Genome Biol. 2017. PMID: 28615073 Free PMC article.

5

Type II-C CRISPR-Cas9 Biology, Mechanism, and Application.

Mir A, Edraki A, Lee J, Sontheimer EJ. Mir A, et al. Among authors: sontheimer ej. ACS Chem Biol. 2018 Feb 16;13(2):357-365. doi: 10.1021/acschembio.7b00855. Epub 2017 Dec 20. ACS Chem Biol. 2018. PMID: 29202216 Free PMC article. Review.

6

C-BERST: defining subnuclear proteomic landscapes at genomic elements with dCas9-APEX2.

Gao XD, Tu LC, Mir A, Rodriguez T, Ding Y, Leszyk J, Dekker J, Shaffer SA, Zhu LJ, Wolfe SA, Sontheimer EJ. Gao XD, et al. Among authors: sontheimer ej. Nat Methods. 2018 Jun;15(6):433-436. doi: 10.1038/s41592-018-0006-2. Epub 2018 May 7. Nat Methods. 2018. PMID: 29735996 Free PMC article.

7

Heavily and fully modified RNAs guide efficient SpyCas9-mediated genome editing.

Mir A, Alterman JF, Hassler MR, Debacker AJ, Hudgens E, Echeverria D, Brodsky MH, Khvorova A, Watts JK, Sontheimer EJ. Mir A, et al. Among authors: sontheimer ej. Nat Commun. 2018 Jul 6;9(1):2641. doi: 10.1038/s41467-018-05073-z. Nat Commun. 2018. PMID: 29980686 Free PMC article.

8

All-in-one adeno-associated virus delivery and genome editing by Neisseria meningitidis Cas9 in vivo.

Ibraheim R, Song CQ, Mir A, Amrani N, Xue W, Sontheimer EJ. Ibraheim R, et al. Among authors: sontheimer ej. Genome Biol. 2018 Sep 19;19(1):137. doi: 10.1186/s13059-018-1515-0. Genome Biol. 2018. PMID: 30231914 Free PMC article.

9

Orthogonal Cas9-Cas9 chimeras provide a versatile platform for genome editing.

Bolukbasi MF, Liu P, Luk K, Kwok SF, Gupta A, Amrani N, Sontheimer EJ, Zhu LJ, Wolfe SA. Bolukbasi MF, et al. Among authors: sontheimer ej. Nat Commun. 2018 Nov 19;9(1):4856. doi: 10.1038/s41467-018-07310-x. Nat Commun. 2018. PMID: 30451839 Free PMC article.

10

Potent Cas9 Inhibition in Bacterial and Human Cells by AcrIIC4 and AcrIIC5 Anti-CRISPR Proteins.

Lee J, Mir A, Edraki A, Garcia B, Amrani N, Lou HE, Gainetdinov I, Pawluk A, Ibraheim R, Gao XD, Liu P, Davidson AR, Maxwell KL, Sontheimer EJ. Lee J, et al. Among authors: sontheimer ej. mBio. 2018 Dec 4;9(6):e02321-18. doi: 10.1128/mBio.02321-18. mBio. 2018. PMID: 30514786 Free PMC article.

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