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Dynamic interactions and Ca2+-binding modulate the holdase-type chaperone activity of S100B preventing tau aggregation and seeding.
Moreira GG, Cantrelle FX, Quezada A, Carvalho FS, Cristóvão JS, Sengupta U, Puangmalai N, Carapeto AP, Rodrigues MS, Cardoso I, Fritz G, Herrera F, Kayed R, Landrieu I, Gomes CM. Moreira GG, et al. Among authors: kayed r. Nat Commun. 2021 Nov 1;12(1):6292. doi: 10.1038/s41467-021-26584-2. Nat Commun. 2021. PMID: 34725360 Free PMC article.
Preparation and characterization of neurotoxic tau oligomers.
Lasagna-Reeves CA, Castillo-Carranza DL, Guerrero-Muoz MJ, Jackson GR, Kayed R. Lasagna-Reeves CA, et al. Among authors: kayed r. Biochemistry. 2010 Nov 30;49(47):10039-41. doi: 10.1021/bi1016233. Epub 2010 Nov 8. Biochemistry. 2010. PMID: 21047142
Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau.
Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Guerrero-Munoz MJ, Kiritoshi T, Neugebauer V, Jackson GR, Kayed R. Lasagna-Reeves CA, et al. Among authors: kayed r. Sci Rep. 2012;2:700. doi: 10.1038/srep00700. Epub 2012 Oct 3. Sci Rep. 2012. PMID: 23050084 Free PMC article.
Dual role of p53 amyloid formation in cancer; loss of function and gain of toxicity.
Lasagna-Reeves CA, Clos AL, Castillo-Carranza D, Sengupta U, Guerrero-Muñoz M, Kelly B, Wagner R, Kayed R. Lasagna-Reeves CA, et al. Among authors: kayed r. Biochem Biophys Res Commun. 2013 Jan 18;430(3):963-8. doi: 10.1016/j.bbrc.2012.11.130. Epub 2012 Dec 19. Biochem Biophys Res Commun. 2013. PMID: 23261448
Design of metastable β-sheet oligomers from natively unstructured peptide.
Guerrero-Muñoz MJ, Castillo-Carranza DL, Sengupta U, White MA, Kayed R. Guerrero-Muñoz MJ, et al. Among authors: kayed r. ACS Chem Neurosci. 2013 Dec 18;4(12):1520-3. doi: 10.1021/cn4001395. Epub 2013 Oct 14. ACS Chem Neurosci. 2013. PMID: 24106878 Free PMC article.
189 results