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Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis.
Matias MI, Yong CS, Foroushani A, Goldsmith C, Mongellaz C, Sezgin E, Levental KR, Talebi A, Perrault J, Rivière A, Dehairs J, Delos O, Bertand-Michel J, Portais JC, Wong M, Marie JC, Kelekar A, Kinet S, Zimmermann VS, Levental I, Yvan-Charvet L, Swinnen JV, Muljo SA, Hernandez-Vargas H, Tardito S, Taylor N, Dardalhon V. Matias MI, et al. Among authors: marie jc. Cell Rep. 2021 Nov 2;37(5):109911. doi: 10.1016/j.celrep.2021.109911. Cell Rep. 2021. PMID: 34731632 Free PMC article.
Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation.
Klysz D, Tai X, Robert PA, Craveiro M, Cretenet G, Oburoglu L, Mongellaz C, Floess S, Fritz V, Matias MI, Yong C, Surh N, Marie JC, Huehn J, Zimmermann V, Kinet S, Dardalhon V, Taylor N. Klysz D, et al. Among authors: marie jc. Sci Signal. 2015 Sep 29;8(396):ra97. doi: 10.1126/scisignal.aab2610. Sci Signal. 2015. PMID: 26420908
An intestinal TH17 cell-derived subset can initiate cancer.
Fesneau O, Thevin V, Pinet V, Goldsmith C, Vieille B, M'Homa Soudja S, Lattanzio R, Hahne M, Dardalhon V, Hernandez-Vargas H, Benech N, Marie JC. Fesneau O, et al. Among authors: marie jc. Nat Immunol. 2024 Sep;25(9):1637-1649. doi: 10.1038/s41590-024-01909-7. Epub 2024 Jul 26. Nat Immunol. 2024. PMID: 39060651 Free PMC article.
ERRα Expression in Bone Metastases Leads to an Exacerbated Antitumor Immune Response.
Bouchet M, Lainé A, Boyault C, Proponnet-Guerault M, Meugnier E, Bouazza L, Kan CWS, Geraci S, El-Moghrabi S, Hernandez-Vargas H, Benetollo C, Yoshiko Y, Duterque-Coquillaud M, Clézardin P, Marie JC, Bonnelye E. Bouchet M, et al. Among authors: marie jc. Cancer Res. 2020 Jul 1;80(13):2914-2926. doi: 10.1158/0008-5472.CAN-19-3584. Epub 2020 May 4. Cancer Res. 2020. PMID: 32366476 Free article.
123 results