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B cell-derived GABA elicits IL-10+ macrophages to limit anti-tumour immunity.
Zhang B, Vogelzang A, Miyajima M, Sugiura Y, Wu Y, Chamoto K, Nakano R, Hatae R, Menzies RJ, Sonomura K, Hojo N, Ogawa T, Kobayashi W, Tsutsui Y, Yamamoto S, Maruya M, Narushima S, Suzuki K, Sugiya H, Murakami K, Hashimoto M, Ueno H, Kobayashi T, Ito K, Hirano T, Shiroguchi K, Matsuda F, Suematsu M, Honjo T, Fagarasan S. Zhang B, et al. Nature. 2021 Nov;599(7885):471-476. doi: 10.1038/s41586-021-04082-1. Epub 2021 Nov 3. Nature. 2021. PMID: 34732892 Free PMC article.
Metabolic shift induced by systemic activation of T cells in PD-1-deficient mice perturbs brain monoamines and emotional behavior.
Miyajima M, Zhang B, Sugiura Y, Sonomura K, Guerrini MM, Tsutsui Y, Maruya M, Vogelzang A, Chamoto K, Honda K, Hikida T, Ito S, Qin H, Sanuki R, Suzuki K, Furukawa T, Ishihama Y, Matsuda F, Suematsu M, Honjo T, Fagarasan S. Miyajima M, et al. Among authors: zhang b. Nat Immunol. 2017 Dec;18(12):1342-1352. doi: 10.1038/ni.3867. Epub 2017 Oct 23. Nat Immunol. 2017. PMID: 29058703
Spermidine activates mitochondrial trifunctional protein and improves antitumor immunity in mice.
Al-Habsi M, Chamoto K, Matsumoto K, Nomura N, Zhang B, Sugiura Y, Sonomura K, Maharani A, Nakajima Y, Wu Y, Nomura Y, Menzies R, Tajima M, Kitaoka K, Haku Y, Delghandi S, Yurimoto K, Matsuda F, Iwata S, Ogura T, Fagarasan S, Honjo T. Al-Habsi M, et al. Among authors: zhang b. Science. 2022 Oct 28;378(6618):eabj3510. doi: 10.1126/science.abj3510. Epub 2022 Oct 28. Science. 2022. PMID: 36302005
Impaired development of memory B cells and antibody responses in humans and mice deficient in PD-1 signaling.
Ogishi M, Kitaoka K, Good-Jacobson KL, Rinchai D, Zhang B, Wang J, Gies V, Rao G, Nguyen T, Avery DT, Khan T, Smithmyer ME, Mackie J, Yang R, Arias AA, Asano T, Ponsin K, Chaldebas M, Zhang P, Peel JN, Bohlen J, Lévy R, Pelham SJ, Lei WT, Han JE, Fagniez I, Chrabieh M, Laine C, Langlais D, Gruber C, Al Ali F, Rahman M, Aytekin C, Benson B, Dufort MJ, Domingo-Vila C, Moriya K, Shlomchik M, Uzel G, Gray PE, Suan D, Preece K, Chua I, Okada S, Chikuma S, Kiyonari H, Tree TI, Bogunovic D, Gros P, Marr N, Speake C, Oram RA, Béziat V, Bustamante J, Abel L, Boisson B, Korganow AS, Ma CS, Johnson MB, Chamoto K, Boisson-Dupuis S, Honjo T, Casanova JL, Tangye SG. Ogishi M, et al. Among authors: zhang b, zhang p. Immunity. 2024 Dec 10;57(12):2790-2807.e15. doi: 10.1016/j.immuni.2024.10.014. Epub 2024 Nov 26. Immunity. 2024. PMID: 39603236
Cell-type specific, inducible and acute degradation of targeted protein in mice by two degron systems.
Yamashita M, Ogawa C, Zhang B, Kobayashi T, Nomura A, Barker C, Zou C, Yamanaka S, Hayashi KI, Shinkai Y, Moro K, Fargarasan S, Imami K, Seita J, Shirai F, Sawasaki T, Kanemaki MT, Taniuchi I. Yamashita M, et al. Among authors: zhang b. Nat Commun. 2024 Nov 29;15(1):10129. doi: 10.1038/s41467-024-54308-9. Nat Commun. 2024. PMID: 39613744 Free PMC article.
Prourokinase vs Standard Care for Patients With Mild Ischemic Stroke: The PUMICE Randomized Clinical Trial.
Xiong Y, Meng X, Jin A, Campbell BCV, Xu A, Dong Q, Xu Y, Pan Y, Jiang Y, Niu S, Li Z, Zhuang X, Guo N, Yuan Z, Kong Z, Zong L, Duan C, Cao Z, Wang L, Hao M, Wu S, Feng X, Li H, Wu N, Li Z, Zhao X, Wang Y; PUMICE Investigators. Xiong Y, et al. JAMA Neurol. 2025 Jan 21. doi: 10.1001/jamaneurol.2024.4688. Online ahead of print. JAMA Neurol. 2025. PMID: 39836393
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