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RNA promotes the formation of spatial compartments in the nucleus.
Quinodoz SA, Jachowicz JW, Bhat P, Ollikainen N, Banerjee AK, Goronzy IN, Blanco MR, Chovanec P, Chow A, Markaki Y, Thai J, Plath K, Guttman M. Quinodoz SA, et al. Among authors: plath k. Cell. 2021 Nov 11;184(23):5775-5790.e30. doi: 10.1016/j.cell.2021.10.014. Epub 2021 Nov 4. Cell. 2021. PMID: 34739832 Free PMC article.
X chromosome reactivation dynamics reveal stages of reprogramming to pluripotency.
Pasque V, Tchieu J, Karnik R, Uyeda M, Sadhu Dimashkie A, Case D, Papp B, Bonora G, Patel S, Ho R, Schmidt R, McKee R, Sado T, Tada T, Meissner A, Plath K. Pasque V, et al. Among authors: plath k. Cell. 2014 Dec 18;159(7):1681-97. doi: 10.1016/j.cell.2014.11.040. Cell. 2014. PMID: 25525883 Free PMC article.
The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3.
McHugh CA, Chen CK, Chow A, Surka CF, Tran C, McDonel P, Pandya-Jones A, Blanco M, Burghard C, Moradian A, Sweredoski MJ, Shishkin AA, Su J, Lander ES, Hess S, Plath K, Guttman M. McHugh CA, et al. Among authors: plath k. Nature. 2015 May 14;521(7551):232-6. doi: 10.1038/nature14443. Epub 2015 Apr 27. Nature. 2015. PMID: 25915022 Free PMC article.
The Role of Xist in X-Chromosome Dosage Compensation.
Sahakyan A, Yang Y, Plath K. Sahakyan A, et al. Among authors: plath k. Trends Cell Biol. 2018 Dec;28(12):999-1013. doi: 10.1016/j.tcb.2018.05.005. Epub 2018 Jun 14. Trends Cell Biol. 2018. PMID: 29910081 Free PMC article. Review.
A protein assembly mediates Xist localization and gene silencing.
Pandya-Jones A, Markaki Y, Serizay J, Chitiashvili T, Mancia Leon WR, Damianov A, Chronis C, Papp B, Chen CK, McKee R, Wang XJ, Chau A, Sabri S, Leonhardt H, Zheng S, Guttman M, Black DL, Plath K. Pandya-Jones A, et al. Among authors: plath k. Nature. 2020 Nov;587(7832):145-151. doi: 10.1038/s41586-020-2703-0. Epub 2020 Sep 9. Nature. 2020. PMID: 32908311 Free PMC article.
Publisher Correction: A protein assembly mediates Xist localization and gene silencing.
Pandya-Jones A, Markaki Y, Serizay J, Chitiashvili T, Leon WRM, Damianov A, Chronis C, Papp B, Chen CK, McKee R, Wang XJ, Chau A, Sabri S, Leonhardt H, Zheng S, Guttman M, Black DL, Plath K. Pandya-Jones A, et al. Among authors: plath k. Nature. 2020 Oct;586(7830):E30. doi: 10.1038/s41586-020-2790-y. Nature. 2020. PMID: 33005055
Xist nucleates local protein gradients to propagate silencing across the X chromosome.
Markaki Y, Gan Chong J, Wang Y, Jacobson EC, Luong C, Tan SYX, Jachowicz JW, Strehle M, Maestrini D, Banerjee AK, Mistry BA, Dror I, Dossin F, Schöneberg J, Heard E, Guttman M, Chou T, Plath K. Markaki Y, et al. Among authors: plath k. Cell. 2021 Dec 9;184(25):6174-6192.e32. doi: 10.1016/j.cell.2021.10.022. Epub 2021 Nov 4. Cell. 2021. PMID: 34813726 Free PMC article.
Xist nucleates local protein gradients to propagate silencing across the X chromosome.
Markaki Y, Chong JG, Wang Y, Jacobson EC, Luong C, Tan SYX, Jachowicz JW, Strehle M, Maestrini D, Banerjee AK, Mistry BA, Dror I, Dossin F, Schӧneberg J, Heard E, Guttman M, Chou T, Plath K. Markaki Y, et al. Among authors: plath k. Cell. 2021 Dec 9;184(25):6212. doi: 10.1016/j.cell.2021.11.028. Cell. 2021. PMID: 34890555 Free PMC article. No abstract available.
XIST directly regulates X-linked and autosomal genes in naive human pluripotent cells.
Dror I, Chitiashvili T, Tan SYX, Cano CT, Sahakyan A, Markaki Y, Chronis C, Collier AJ, Deng W, Liang G, Sun Y, Afasizheva A, Miller J, Xiao W, Black DL, Ding F, Plath K. Dror I, et al. Among authors: plath k. Cell. 2024 Jan 4;187(1):110-129.e31. doi: 10.1016/j.cell.2023.11.033. Cell. 2024. PMID: 38181737 Free article.
159 results