Shi J - Search Results

1

Plasma Carboxylesterase 1 Predicts Methylphenidate Exposure: A Proof-of-Concept Study Using Plasma Protein Biomarker for Hepatic Drug Metabolism.

Shi J, Xiao J, Wang X, Jung SM, Bleske BE, Markowitz JS, Patrick KS, Zhu HJ. Shi J, et al. Clin Pharmacol Ther. 2022 Apr;111(4):878-885. doi: 10.1002/cpt.2486. Epub 2021 Nov 30. Clin Pharmacol Ther. 2022. PMID: 34743324 Free PMC article.

2

Impact of carboxylesterase 1 genetic polymorphism on trandolapril activation in human liver and the pharmacokinetics and pharmacodynamics in healthy volunteers.

Wang X, Her L, Xiao J, Shi J, Wu AH, Bleske BE, Zhu HJ. Wang X, et al. Among authors: shi j. Clin Transl Sci. 2021 Jul;14(4):1380-1389. doi: 10.1111/cts.12989. Epub 2021 Mar 4. Clin Transl Sci. 2021. PMID: 33660934 Free PMC article. Clinical Trial.

3

Contributions of Cathepsin A and Carboxylesterase 1 to the Hydrolysis of Tenofovir Alafenamide in the Human Liver, and the Effect of CES1 Genetic Variation on Tenofovir Alafenamide Hydrolysis.

Li J, Shi J, Xiao J, Tran L, Wang X, Zhu HJ. Li J, et al. Among authors: shi j. Drug Metab Dispos. 2022 Mar;50(3):243-248. doi: 10.1124/dmd.120.000323. Epub 2021 Dec 21. Drug Metab Dispos. 2022. PMID: 34933885 Free PMC article.

4

Physiologically-Based Pharmacokinetic Modeling to Predict Methylphenidate Exposure Affected by Interplay Among Carboxylesterase 1 Pharmacogenetics, Drug-Drug Interactions, and Sex.

Xiao J, Shi J, Thompson BR, Smith DE, Zhang T, Zhu HJ. Xiao J, et al. Among authors: shi j. J Pharm Sci. 2022 Sep;111(9):2606-2613. doi: 10.1016/j.xphs.2022.04.019. Epub 2022 May 6. J Pharm Sci. 2022. PMID: 35526575 Free PMC article.

5

Association of Oseltamivir Activation with Gender and Carboxylesterase 1 Genetic Polymorphisms.

Shi J, Wang X, Eyler RF, Liang Y, Liu L, Mueller BA, Zhu HJ. Shi J, et al. Basic Clin Pharmacol Toxicol. 2016 Dec;119(6):555-561. doi: 10.1111/bcpt.12625. Epub 2016 Jul 21. Basic Clin Pharmacol Toxicol. 2016. PMID: 27228223 Free PMC article.

6

Dabigatran etexilate activation is affected by the CES1 genetic polymorphism G143E (rs71647871) and gender.

Shi J, Wang X, Nguyen JH, Bleske BE, Liang Y, Liu L, Zhu HJ. Shi J, et al. Biochem Pharmacol. 2016 Nov 1;119:76-84. doi: 10.1016/j.bcp.2016.09.003. Epub 2016 Sep 8. Biochem Pharmacol. 2016. PMID: 27614009 Free PMC article.

7

A Comprehensive Functional Assessment of Carboxylesterase 1 Nonsynonymous Polymorphisms.

Wang X, Rida N, Shi J, Wu AH, Bleske BE, Zhu HJ. Wang X, et al. Among authors: shi j. Drug Metab Dispos. 2017 Nov;45(11):1149-1155. doi: 10.1124/dmd.117.077669. Epub 2017 Aug 24. Drug Metab Dispos. 2017. PMID: 28838926 Free PMC article.

8

Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation.

Shi J, Wang X, Nguyen J, Wu AH, Bleske BE, Zhu HJ. Shi J, et al. Drug Metab Dispos. 2016 Apr;44(4):554-9. doi: 10.1124/dmd.115.068536. Epub 2016 Jan 27. Drug Metab Dispos. 2016. PMID: 26817948 Free PMC article.

9

Pharmacokinetics of gemcitabine and its amino acid ester prodrug following intravenous and oral administrations in mice.

Thompson BR, Shi J, Zhu HJ, Smith DE. Thompson BR, et al. Among authors: shi j. Biochem Pharmacol. 2020 Oct;180:114127. doi: 10.1016/j.bcp.2020.114127. Epub 2020 Jun 27. Biochem Pharmacol. 2020. PMID: 32603666 Free PMC article.

10

Tissue-Specific Proteomics Analysis of Anti-COVID-19 Nucleoside and Nucleotide Prodrug-Activating Enzymes Provides Insights into the Optimization of Prodrug Design and Pharmacotherapy Strategy.

Li J, Liu S, Shi J, Wang X, Xue Y, Zhu HJ. Li J, et al. Among authors: shi j. ACS Pharmacol Transl Sci. 2021 Apr 1;4(2):870-887. doi: 10.1021/acsptsci.1c00016. eCollection 2021 Apr 9. ACS Pharmacol Transl Sci. 2021. PMID: 33855276 Free PMC article.

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