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Inhibition of Vascular Smooth Muscle and Cancer Cell Proliferation by New VEGFR Inhibitors and Their Immunomodulator Effect: Design, Synthesis, and Biological Evaluation.
Ran F, Li W, Qin Y, Yu T, Liu Z, Zhou M, Liu C, Qiao T, Li X, Yousef RG, Eissa IH, Khalifa MM. Ran F, et al. Among authors: khalifa mm. Oxid Med Cell Longev. 2021 Oct 28;2021:8321400. doi: 10.1155/2021/8321400. eCollection 2021. Oxid Med Cell Longev. 2021. PMID: 34745424 Free PMC article.
Design, synthesis, molecular modeling, in vivo studies and anticancer activity evaluation of new phthalazine derivatives as potential DNA intercalators and topoisomerase II inhibitors.
El-Helby AA, Sakr H, Ayyad RR, Mahdy HA, Khalifa MM, Belal A, Rashed M, El-Sharkawy A, Metwaly AM, Elhendawy MA, Radwan MM, ElSohly MA, Eissa IH. El-Helby AA, et al. Among authors: khalifa mm. Bioorg Chem. 2020 Oct;103:104233. doi: 10.1016/j.bioorg.2020.104233. Epub 2020 Aug 26. Bioorg Chem. 2020. PMID: 32882440
New benzoxazole derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, anti-proliferative evaluation, flowcytometric analysis, and in silico studies.
Elkady H, Elwan A, El-Mahdy HA, Doghish AS, Ismail A, Taghour MS, Elkaeed EB, Eissa IH, Dahab MA, Mahdy HA, Khalifa MM. Elkady H, et al. Among authors: khalifa mm. J Enzyme Inhib Med Chem. 2022 Dec;37(1):397-410. doi: 10.1080/14756366.2021.2015343. J Enzyme Inhib Med Chem. 2022. PMID: 34961427 Free PMC article.
Discovery of new nicotinamides as apoptotic VEGFR-2 inhibitors: virtual screening, synthesis, anti-proliferative, immunomodulatory, ADMET, toxicity, and molecular dynamic simulation studies.
Yousef RG, Ibrahim A, Khalifa MM, Eldehna WM, Gobaara IMM, Mehany ABM, Elkaeed EB, Alsfouk AA, Metwaly AM, Eissa IH. Yousef RG, et al. Among authors: khalifa mm. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1389-1403. doi: 10.1080/14756366.2022.2070744. J Enzyme Inhib Med Chem. 2022. PMID: 35577416 Free PMC article.
157 results