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A structural ensemble of a ribosome-nascent chain complex during cotranslational protein folding.
Cabrita LD, Cassaignau AME, Launay HMM, Waudby CA, Wlodarski T, Camilloni C, Karyadi ME, Robertson AL, Wang X, Wentink AS, Goodsell L, Woolhead CA, Vendruscolo M, Dobson CM, Christodoulou J. Cabrita LD, et al. Among authors: cassaignau ame. Nat Struct Mol Biol. 2016 Apr;23(4):278-285. doi: 10.1038/nsmb.3182. Epub 2016 Feb 29. Nat Struct Mol Biol. 2016. PMID: 26926436 Free PMC article.
How Does the Ribosome Fold the Proteome?
Cassaignau AME, Cabrita LD, Christodoulou J. Cassaignau AME, et al. Annu Rev Biochem. 2020 Jun 20;89:389-415. doi: 10.1146/annurev-biochem-062917-012226. Annu Rev Biochem. 2020. PMID: 32569518 Review.
Common sequence motifs of nascent chains engage the ribosome surface and trigger factor.
Deckert A, Cassaignau AME, Wang X, Włodarski T, Chan SHS, Waudby CA, Kirkpatrick JP, Vendruscolo M, Cabrita LD, Christodoulou J. Deckert A, et al. Among authors: cassaignau ame. Proc Natl Acad Sci U S A. 2021 Dec 28;118(52):e2103015118. doi: 10.1073/pnas.2103015118. Proc Natl Acad Sci U S A. 2021. PMID: 34930833 Free PMC article.
Modulating co-translational protein folding by rational design and ribosome engineering.
Ahn M, Włodarski T, Mitropoulou A, Chan SHS, Sidhu H, Plessa E, Becker TA, Budisa N, Waudby CA, Beckmann R, Cassaignau AME, Cabrita LD, Christodoulou J. Ahn M, et al. Among authors: cassaignau ame. Nat Commun. 2022 Jul 22;13(1):4243. doi: 10.1038/s41467-022-31906-z. Nat Commun. 2022. PMID: 35869078 Free PMC article.
The ribosome stabilizes partially folded intermediates of a nascent multi-domain protein.
Chan SHS, Włodarski T, Streit JO, Cassaignau AME, Woodburn LF, Ahn M, Freiherr von Sass GJ, Waudby CA, Budisa N, Cabrita LD, Christodoulou J. Chan SHS, et al. Among authors: cassaignau ame. Nat Chem. 2022 Oct;14(10):1165-1173. doi: 10.1038/s41557-022-01004-0. Epub 2022 Aug 4. Nat Chem. 2022. PMID: 35927328 Free PMC article.
14 results