Ito KR - Search Results

1

Drug discovery and development scheme for liver-targeting bridged nucleic acid antisense oligonucleotides.

Wada F, Yamamoto T, Kobayashi T, Tachibana K, Ito KR, Hamasaki M, Kayaba Y, Terada C, Yamayoshi A, Obika S, Harada-Shiba M. Wada F, et al. Among authors: ito kr. Mol Ther Nucleic Acids. 2021 Oct 19;26:957-969. doi: 10.1016/j.omtn.2021.10.008. eCollection 2021 Dec 3. Mol Ther Nucleic Acids. 2021. PMID: 34760338 Free PMC article.

2

Double-stranded DNA-templated cleavage of oligonucleotides containing a P3'->N5' linkage triggered by triplex formation: the effects of chemical modifications and remarkable enhancement in reactivity.

Ito KR, Kodama T, Tomizu M, Negoro Y, Orita A, Osaki T, Hosoki N, Tanaka T, Imanishi T, Obika S. Ito KR, et al. Nucleic Acids Res. 2010 Nov;38(20):7332-42. doi: 10.1093/nar/gkq600. Epub 2010 Jul 8. Nucleic Acids Res. 2010. PMID: 20615902 Free PMC article.

3

Hybridization and Mismatch Discrimination Abilities of 2',4'-Bridged Nucleic Acids Bearing 2-Thiothymine or 2-Selenothymine Nucleobase.

Habuchi T, Yamaguchi T, Aoyama H, Horiba M, Ito KR, Obika S. Habuchi T, et al. Among authors: ito kr. J Org Chem. 2019 Feb 1;84(3):1430-1439. doi: 10.1021/acs.joc.8b02863. Epub 2019 Jan 24. J Org Chem. 2019. PMID: 30632750

4

In vitro and in vivo biophysical properties of oligonucleotides containing 5'-thio nucleosides.

Islam MA, Waki R, Fujisaka A, Ito KR, Obika S. Islam MA, et al. Among authors: ito kr. Drug Discov Ther. 2016;10(5):263-270. doi: 10.5582/ddt.2016.01055. Drug Discov Ther. 2016. PMID: 27890900 Free article.

5

Synthesis and Properties of 7-Deazapurine- and 8-Aza-7-deazapurine-Locked Nucleic Acid Analogues: Effect of the Glycosidic Torsion Angle.

Hara T, Kodama T, Takegaki Y, Morihiro K, Ito KR, Obika S. Hara T, et al. Among authors: ito kr. J Org Chem. 2017 Jan 6;82(1):25-36. doi: 10.1021/acs.joc.6b02525. Epub 2016 Dec 15. J Org Chem. 2017. PMID: 27958739

6

Synthesis and biophysical properties of 5'-thio-2',4'-BNA/LNA oligonucleotide.

Islam MA, Fujisaka A, Mori S, Ito KR, Yamaguchi T, Obika S. Islam MA, et al. Among authors: ito kr. Bioorg Med Chem. 2018 Jul 23;26(12):3634-3638. doi: 10.1016/j.bmc.2018.05.040. Epub 2018 May 23. Bioorg Med Chem. 2018. PMID: 29886084

7

Cleavage of oligonucleotides containing a P3'→N5' phosphoramidate linkage mediated by single-stranded oligonucleotide templates.

Ito KR, Kodama T, Makimura F, Hosoki N, Osaki T, Orita A, Imanishi T, Obika S. Ito KR, et al. Molecules. 2011 Dec 20;16(12):10695-708. doi: 10.3390/molecules161210695. Molecules. 2011. PMID: 22186956 Free PMC article.

8

Considerations of the Japanese Research Working Group for the ICH S6 & Related Issues Regarding Nonclinical Safety Assessments of Oligonucleotide Therapeutics: Comparison with Those of Biopharmaceuticals.

Hirabayashi Y, Maki K, Kinoshita K, Nakazawa T, Obika S, Naota M, Watanabe K, Suzuki M, Arato T, Fujisaka A, Fueki O, Ito K, Onodera H. Hirabayashi Y, et al. Nucleic Acid Ther. 2021 Apr;31(2):114-125. doi: 10.1089/nat.2020.0879. Epub 2021 Jan 19. Nucleic Acid Ther. 2021. PMID: 33470890 Free PMC article.

9

Possible roles of human mast cells in the formation of xanthelasma palpebrarum.

Nakamura H, Matsuzaki T, Ito KR, Nakagawa R, Asano LM, Nishikido H, Haga H, Kataoka TR. Nakamura H, et al. Among authors: ito kr. Pathol Int. 2023 Sep;73(9):406-412. doi: 10.1111/pin.13347. Epub 2023 Jun 21. Pathol Int. 2023. PMID: 37341622

10

Evaluation of post-colostrum ingestion changes in the protein composition of peripheral blood of newborn piglets: A pilot study.

Ito KR, Kawasaki K, Miura H, Tsukahara T, Inoue R. Ito KR, et al. Anim Sci J. 2022 Jan-Dec;93(1):e13783. doi: 10.1111/asj.13783. Anim Sci J. 2022. PMID: 36502277

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