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Control of lysosomal-mediated cell death by the pH-dependent calcium channel RECS1.
Pihán P, Lisbona F, Borgonovo J, Edwards-Jorquera S, Nunes-Hasler P, Castillo K, Kepp O, Urra H, Saarnio S, Vihinen H, Carreras-Sureda A, Forveille S, Sauvat A, De Giorgis D, Pupo A, Rodríguez DA, Quarato G, Sagredo A, Lourido F, Letai A, Latorre R, Kroemer G, Demaurex N, Jokitalo E, Concha ML, Glavic Á, Green DR, Hetz C. Pihán P, et al. Among authors: urra h. Sci Adv. 2021 Nov 12;7(46):eabe5469. doi: 10.1126/sciadv.abe5469. Epub 2021 Nov 12. Sci Adv. 2021. PMID: 34767445 Free PMC article.
IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A.
Urra H, Henriquez DR, Cánovas J, Villarroel-Campos D, Carreras-Sureda A, Pulgar E, Molina E, Hazari YM, Limia CM, Alvarez-Rojas S, Figueroa R, Vidal RL, Rodriguez DA, Rivera CA, Court FA, Couve A, Qi L, Chevet E, Akai R, Iwawaki T, Concha ML, Glavic Á, Gonzalez-Billault C, Hetz C. Urra H, et al. Nat Cell Biol. 2018 Aug;20(8):942-953. doi: 10.1038/s41556-018-0141-0. Epub 2018 Jul 16. Nat Cell Biol. 2018. PMID: 30013108
Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response.
Dufey E, Bravo-San Pedro JM, Eggers C, González-Quiroz M, Urra H, Sagredo AI, Sepulveda D, Pihán P, Carreras-Sureda A, Hazari Y, Sagredo EA, Gutierrez D, Valls C, Papaioannou A, Acosta-Alvear D, Campos G, Domingos PM, Pedeux R, Chevet E, Alvarez A, Godoy P, Walter P, Glavic A, Kroemer G, Hetz C. Dufey E, et al. Among authors: urra h. Nat Commun. 2020 May 14;11(1):2401. doi: 10.1038/s41467-020-15694-y. Nat Commun. 2020. PMID: 32409639 Free PMC article.
Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics.
Carreras-Sureda A, Jaña F, Urra H, Durand S, Mortenson DE, Sagredo A, Bustos G, Hazari Y, Ramos-Fernández E, Sassano ML, Pihán P, van Vliet AR, González-Quiroz M, Torres AK, Tapia-Rojas C, Kerkhofs M, Vicente R, Kaufman RJ, Inestrosa NC, Gonzalez-Billault C, Wiseman RL, Agostinis P, Bultynck G, Court FA, Kroemer G, Cárdenas JC, Hetz C. Carreras-Sureda A, et al. Among authors: urra h. Nat Cell Biol. 2019 Jun;21(6):755-767. doi: 10.1038/s41556-019-0329-y. Epub 2019 May 20. Nat Cell Biol. 2019. PMID: 31110288 Free PMC article.
Author Correction: IRE1α governs cytoskeleton remodeling and cell migration through a direct interaction with filamin A.
Urra H, Henriquez DR, Cánovas J, Villarroel-Campos D, Carreras-Sureda A, Pulgar E, Molina E, Hazari YM, Limia CM, Alvarez-Rojas S, Figueroa R, Vidal RL, Rodriguez DA, Rivera CA, Court FA, Couve A, Qi L, Chevet E, Akai R, Iwawaki T, Concha ML, Glavic Á, Gonzalez-Billault C, Hetz C. Urra H, et al. Nat Cell Biol. 2021 May;23(5):577. doi: 10.1038/s41556-021-00673-2. Nat Cell Biol. 2021. PMID: 33907311 No abstract available.
BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α.
Rodriguez DA, Zamorano S, Lisbona F, Rojas-Rivera D, Urra H, Cubillos-Ruiz JR, Armisen R, Henriquez DR, Cheng EH, Letek M, Vaisar T, Irrazabal T, Gonzalez-Billault C, Letai A, Pimentel-Muiños FX, Kroemer G, Hetz C. Rodriguez DA, et al. Among authors: urra h. EMBO J. 2012 May 16;31(10):2322-35. doi: 10.1038/emboj.2012.84. Epub 2012 Apr 17. EMBO J. 2012. PMID: 22510886 Free PMC article.
When ER stress reaches a dead end.
Urra H, Dufey E, Lisbona F, Rojas-Rivera D, Hetz C. Urra H, et al. Biochim Biophys Acta. 2013 Dec;1833(12):3507-3517. doi: 10.1016/j.bbamcr.2013.07.024. Epub 2013 Aug 27. Biochim Biophys Acta. 2013. PMID: 23988738 Free article. Review.
35 results