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The effect of peroxynitrite decomposition catalyst MnTBAP on aldehyde dehydrogenase-2 nitration by organic nitrates: role in nitrate tolerance.
Mollace V, Muscoli C, Dagostino C, Giancotti LA, Gliozzi M, Sacco I, Visalli V, Gratteri S, Palma E, Malara N, Musolino V, Carresi C, Muscoli S, Vitale C, Salvemini D, Romeo F. Mollace V, et al. Among authors: giancotti la. Pharmacol Res. 2014 Nov;89:29-35. doi: 10.1016/j.phrs.2014.07.007. Epub 2014 Aug 28. Pharmacol Res. 2014. PMID: 25174989
Inhibition of Spinal Oxidative Stress by Bergamot Polyphenolic Fraction Attenuates the Development of Morphine Induced Tolerance and Hyperalgesia in Mice.
Lauro F, Giancotti LA, Ilari S, Dagostino C, Gliozzi M, Morabito C, Malafoglia V, Raffaeli W, Muraca M, Goffredo BM, Mollace V, Muscoli C. Lauro F, et al. Among authors: giancotti la. PLoS One. 2016 May 26;11(5):e0156039. doi: 10.1371/journal.pone.0156039. eCollection 2016. PLoS One. 2016. PMID: 27227548 Free PMC article.
Dysregulation of sphingolipid metabolism contributes to bortezomib-induced neuropathic pain.
Stockstill K, Doyle TM, Yan X, Chen Z, Janes K, Little JW, Braden K, Lauro F, Giancotti LA, Harada CM, Yadav R, Xiao WH, Lionberger JM, Neumann WL, Bennett GJ, Weng HR, Spiegel S, Salvemini D. Stockstill K, et al. Among authors: giancotti la. J Exp Med. 2018 May 7;215(5):1301-1313. doi: 10.1084/jem.20170584. Epub 2018 Apr 27. J Exp Med. 2018. PMID: 29703731 Free PMC article.
Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain.
Chen Z, Doyle TM, Luongo L, Largent-Milnes TM, Giancotti LA, Kolar G, Squillace S, Boccella S, Walker JK, Pendleton A, Spiegel S, Neumann WL, Vanderah TW, Salvemini D. Chen Z, et al. Among authors: giancotti la. Proc Natl Acad Sci U S A. 2019 May 21;116(21):10557-10562. doi: 10.1073/pnas.1820466116. Epub 2019 May 8. Proc Natl Acad Sci U S A. 2019. PMID: 31068460 Free PMC article.
GPR160 de-orphanization reveals critical roles in neuropathic pain in rodents.
Yosten GL, Harada CM, Haddock C, Giancotti LA, Kolar GR, Patel R, Guo C, Chen Z, Zhang J, Doyle TM, Dickenson AH, Samson WK, Salvemini D. Yosten GL, et al. Among authors: giancotti la. J Clin Invest. 2020 May 1;130(5):2587-2592. doi: 10.1172/JCI133270. J Clin Invest. 2020. PMID: 31999650 Free PMC article.
Antioxidant modulation of sirtuin 3 during acute inflammatory pain: The ROS control.
Ilari S, Giancotti LA, Lauro F, Dagostino C, Gliozzi M, Malafoglia V, Sansone L, Palma E, Tafani M, Russo MA, Tomino C, Fini M, Salvemini D, Mollace V, Muscoli C. Ilari S, et al. Among authors: giancotti la. Pharmacol Res. 2020 Jul;157:104851. doi: 10.1016/j.phrs.2020.104851. Epub 2020 May 11. Pharmacol Res. 2020. PMID: 32423865 Free article.
P2Y14 Receptor Antagonists Reverse Chronic Neuropathic Pain in a Mouse Model.
Mufti F, Jung YH, Giancotti LA, Yu J, Chen Z, Phung NB, Jacobson KA, Salvemini D. Mufti F, et al. Among authors: giancotti la. ACS Med Chem Lett. 2020 Apr 30;11(6):1281-1286. doi: 10.1021/acsmedchemlett.0c00115. eCollection 2020 Jun 11. ACS Med Chem Lett. 2020. PMID: 32551012 Free PMC article.
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