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Melanoma secretion of transforming growth factor-β2 leads to loss of epidermal AMBRA1 threatening epidermal integrity and facilitating tumour ulceration.
Cosgarea I, McConnell AT, Ewen T, Tang D, Hill DS, Anagnostou M, Elias M, Ellis RA, Murray A, Spender LC, Giglio P, Gagliardi M, Greenwood A, Piacentini M, Inman GJ, Fimia GM, Corazzari M, Armstrong JL, Lovat PE. Cosgarea I, et al. Among authors: mcconnell at. Br J Dermatol. 2022 Apr;186(4):694-704. doi: 10.1111/bjd.20889. Epub 2021 Dec 27. Br J Dermatol. 2022. PMID: 34773645 Free PMC article.
Epidermal autophagy and beclin 1 regulator 1 and loricrin: a paradigm shift in the prognostication and stratification of the American Joint Committee on Cancer stage I melanomas.
Ellis R, Tang D, Nasr B, Greenwood A, McConnell A, Anagnostou ME, Elias M, Verykiou S, Bajwa D, Ewen T, Reynolds NJ, Barrett P, Carling E, Watson G, Armstrong J, Allen AJ, Horswell S, Labus M, Lovat PE. Ellis R, et al. Br J Dermatol. 2020 Jan;182(1):156-165. doi: 10.1111/bjd.18086. Epub 2019 Jun 19. Br J Dermatol. 2020. PMID: 31056744 Free PMC article.