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A novel small molecule inhibitor of human Drp1.
Rosdah AA, Abbott BM, Langendorf CG, Deng Y, Truong JQ, Waddell HMM, Ling NXY, Smiles WJ, Delbridge LMD, Liu GS, Oakhill JS, Lim SY, Holien JK. Rosdah AA, et al. Among authors: holien jk. Sci Rep. 2022 Dec 13;12(1):21531. doi: 10.1038/s41598-022-25464-z. Sci Rep. 2022. PMID: 36513726 Free PMC article.
A structural view of PA2G4 isoforms with opposing functions in cancer.
Stevenson BW, Gorman MA, Koach J, Cheung BB, Marshall GM, Parker MW, Holien JK. Stevenson BW, et al. Among authors: holien jk. J Biol Chem. 2020 Nov 20;295(47):16100-16112. doi: 10.1074/jbc.REV120.014293. Epub 2020 Sep 20. J Biol Chem. 2020. PMID: 32952126 Free PMC article. Review.
Inhibitors of the Oncogenic PA2G4-MYCN Protein-Protein Interface.
Massudi H, Luo JS, Holien JK, Gadde S, Krishan S, Herath M, Koach J, Stevenson BW, Gorman MA, Venkat P, Mayoh C, Luo XQ, Parker MW, Cheung BB, Marshall GM. Massudi H, et al. Among authors: holien jk. Cancers (Basel). 2023 Mar 17;15(6):1822. doi: 10.3390/cancers15061822. Cancers (Basel). 2023. PMID: 36980710 Free PMC article.
Direct involvement of the TEN domain at the active site of human telomerase.
Jurczyluk J, Nouwens AS, Holien JK, Adams TE, Lovrecz GO, Parker MW, Cohen SB, Bryan TM. Jurczyluk J, et al. Among authors: holien jk. Nucleic Acids Res. 2011 Mar;39(5):1774-88. doi: 10.1093/nar/gkq1083. Epub 2010 Nov 3. Nucleic Acids Res. 2011. PMID: 21051362 Free PMC article.
61 results