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Lipofuscin causes atypical necroptosis through lysosomal membrane permeabilization.
Pan C, Banerjee K, Lehmann GL, Almeida D, Hajjar KA, Benedicto I, Jiang Z, Radu RA, Thompson DH, Rodriguez-Boulan E, Nociari MM. Pan C, et al. Among authors: nociari mm. Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2100122118. doi: 10.1073/pnas.2100122118. Proc Natl Acad Sci U S A. 2021. PMID: 34782457 Free PMC article.
Beta cyclodextrins bind, stabilize, and remove lipofuscin bisretinoids from retinal pigment epithelium.
Nociari MM, Lehmann GL, Perez Bay AE, Radu RA, Jiang Z, Goicochea S, Schreiner R, Warren JD, Shan J, Adam de Beaumais S, Ménand M, Sollogoub M, Maxfield FR, Rodriguez-Boulan E. Nociari MM, et al. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):E1402-8. doi: 10.1073/pnas.1400530111. Epub 2014 Mar 24. Proc Natl Acad Sci U S A. 2014. PMID: 24706818 Free PMC article.
18 results