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An HLA-I signature favouring KIR-educated Natural Killer cells mediates immune control of HIV in children and contrasts with the HLA-B-restricted CD8+ T-cell-mediated immune control in adults.
Vieira VA, Adland E, Malone DFG, Martin MP, Groll A, Ansari MA, Garcia-Guerrero MC, Puertas MC, Muenchhoff M, Guash CF, Brander C, Martinez-Picado J, Bamford A, Tudor-Williams G, Ndung'u T, Walker BD, Ramsuran V, Frater J, Jooste P, Peppa D, Carrington M, Goulder PJR. Vieira VA, et al. Among authors: ramsuran v. PLoS Pathog. 2021 Nov 18;17(11):e1010090. doi: 10.1371/journal.ppat.1010090. eCollection 2021 Nov. PLoS Pathog. 2021. PMID: 34793581 Free PMC article.
Genetic interplay between HLA-C and MIR148A in HIV control and Crohn disease.
Kulkarni S, Qi Y, O'hUigin C, Pereyra F, Ramsuran V, McLaren P, Fellay J, Nelson G, Chen H, Liao W, Bass S, Apps R, Gao X, Yuki Y, Lied A, Ganesan A, Hunt PW, Deeks SG, Wolinsky S, Walker BD, Carrington M. Kulkarni S, et al. Among authors: ramsuran v. Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20705-10. doi: 10.1073/pnas.1312237110. Epub 2013 Nov 18. Proc Natl Acad Sci U S A. 2013. PMID: 24248364 Free PMC article. Clinical Trial.
Effect of female genital schistosomiasis and anti-schistosomal treatment on monocytes, CD4+ T-cells and CCR5 expression in the female genital tract.
Kleppa E, Ramsuran V, Zulu S, Karlsen GH, Bere A, Passmore JA, Ndhlovu P, Lillebø K, Holmen SD, Onsrud M, Gundersen SG, Taylor M, Kjetland EF, Ndung'u T. Kleppa E, et al. Among authors: ramsuran v. PLoS One. 2014 Jun 4;9(6):e98593. doi: 10.1371/journal.pone.0098593. eCollection 2014. PLoS One. 2014. PMID: 24896815 Free PMC article.
Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor.
Gornalusse GG, Mummidi S, Gaitan AA, Jimenez F, Ramsuran V, Picton A, Rogers K, Manoharan MS, Avadhanam N, Murthy KK, Martinez H, Molano Murillo A, Chykarenko ZA, Hutt R, Daskalakis D, Shostakovich-Koretskaya L, Abdool Karim S, Martin JN, Deeks SG, Hecht F, Sinclair E, Clark RA, Okulicz J, Valentine FT, Martinson N, Tiemessen CT, Ndung'u T, Hunt PW, He W, Ahuja SK. Gornalusse GG, et al. Among authors: ramsuran v. Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):E4762-71. doi: 10.1073/pnas.1423228112. Epub 2015 Aug 11. Proc Natl Acad Sci U S A. 2015. PMID: 26307764 Free PMC article.
Elevated HLA-A expression impairs HIV control through inhibition of NKG2A-expressing cells.
Ramsuran V, Naranbhai V, Horowitz A, Qi Y, Martin MP, Yuki Y, Gao X, Walker-Sperling V, Del Prete GQ, Schneider DK, Lifson JD, Fellay J, Deeks SG, Martin JN, Goedert JJ, Wolinsky SM, Michael NL, Kirk GD, Buchbinder S, Haas D, Ndung'u T, Goulder P, Parham P, Walker BD, Carlson JM, Carrington M. Ramsuran V, et al. Science. 2018 Jan 5;359(6371):86-90. doi: 10.1126/science.aam8825. Epub 2018 Jan 4. Science. 2018. PMID: 29302013 Free PMC article.
60 results