Wu BN - Search Results

1

Eugenosedin-A improves obesity-related hyperglycemia by regulating ATP-sensitive K⁺ channels and insulin secretion in pancreatic β cells.

Lin RJ, Yen YK, Lee CH, Hsieh SL, Chang YC, Juan YS, Long CY, Shen KP, Wu BN. Lin RJ, et al. Among authors: wu bn. Biomed Pharmacother. 2022 Jan;145:112447. doi: 10.1016/j.biopha.2021.112447. Epub 2021 Nov 19. Biomed Pharmacother. 2022. PMID: 34808553 Free article.

2

KMUP-1 relaxes rabbit corpus cavernosum smooth muscle in vitro and in vivo: involvement of cyclic GMP and K(+) channels.

Lin RJ, Wu BN, Lo YC, Shen KP, Lin YT, Huang CH, Chen IJ. Lin RJ, et al. Among authors: wu bn. Br J Pharmacol. 2002 Mar;135(5):1159-66. doi: 10.1038/sj.bjp.0704554. Br J Pharmacol. 2002. PMID: 11877322 Free PMC article.

3

KMUP-1, a xanthine derivative, induces relaxation of guinea-pig isolated trachea: the role of the epithelium, cyclic nucleotides and K+ channels.

Wu BN, Lin RJ, Lo YC, Shen KP, Wang CC, Lin YT, Chen IJ. Wu BN, et al. Br J Pharmacol. 2004 Aug;142(7):1105-14. doi: 10.1038/sj.bjp.0705791. Epub 2004 Jul 5. Br J Pharmacol. 2004. PMID: 15237094 Free PMC article.

4

Endothelium-dependent and -independent vasorelaxation by a theophylline derivative MCPT: roles of cyclic nucleotides, potassium channel opening and phosphodiesterase inhibition.

Lo YC, Tsou HH, Lin RJ, Wu DC, Wu BN, Lin YT, Chen IJ. Lo YC, et al. Among authors: wu dc, wu bn. Life Sci. 2005 Jan 7;76(8):931-44. doi: 10.1016/j.lfs.2004.10.009. Life Sci. 2005. PMID: 15589969

5

Aortic smooth muscle relaxants KMUP-3 and KMUP-4, two nitrophenylpiperazine derivatives of xanthine, display cGMP-enhancing activity: roles of endothelium, phosphodiesterase, and K+ channel.

Wu BN, Chen IC, Lin RJ, Chiu CC, An LM, Chen IJ. Wu BN, et al. J Cardiovasc Pharmacol. 2005 Nov;46(5):600-8. doi: 10.1097/01.fjc.0000180900.32489.f9. J Cardiovasc Pharmacol. 2005. PMID: 16220066

6

A xanthine-based epithelium-dependent airway relaxant KMUP-3 (7-[2-[4-(4-nitrobenzene)piperazinyl]ethyl]-1,3-dimethylxanthine) increases respiratory performance and protects against tumor necrosis factor-alpha-induced tracheal contraction, involving nitric oxide release and expression of cGMP and protein kinase G.

Lin RJ, Wu BN, Lo YC, An LM, Dai ZK, Lin YT, Tang CS, Chen IJ. Lin RJ, et al. Among authors: wu bn. J Pharmacol Exp Ther. 2006 Feb;316(2):709-17. doi: 10.1124/jpet.105.092171. Epub 2005 Oct 18. J Pharmacol Exp Ther. 2006. PMID: 16234412

7

Eugenosedin-A amelioration of lipopolysaccharide-induced up-regulation of p38 MAPK, inducible nitric oxide synthase and cyclooxygenase-2.

Shen KP, Liou SF, Hsieh SL, Chen IJ, Wu BN. Shen KP, et al. Among authors: wu bn. J Pharm Pharmacol. 2007 Jun;59(6):879-89. doi: 10.1211/jpp.59.6.0015. J Pharm Pharmacol. 2007. PMID: 17637181

8

Hypotensive and antiaggregative effects of eugenosedin-B with serotonin and alpha/beta-adrenoceptor antagonistic activities in rats and human platelets.

Shen KP, Chu LW, Hsieh SL, An LM, Chen IJ, Wu BN. Shen KP, et al. Among authors: wu bn. J Cardiovasc Pharmacol. 2008 Feb;51(2):154-61. doi: 10.1097/FJC.0b013e31815e852c. J Cardiovasc Pharmacol. 2008. PMID: 18287883

9

Anticancer activity of isoobtusilactone A from Cinnamomum kotoense: involvement of apoptosis, cell-cycle dysregulation, mitochondria regulation, and reactive oxygen species.

Chen CY, Chen CH, Lo YC, Wu BN, Wang HM, Lo WL, Yen CM, Lin RJ. Chen CY, et al. Among authors: wu bn. J Nat Prod. 2008 Jun;71(6):933-40. doi: 10.1021/np070620e. Epub 2008 May 20. J Nat Prod. 2008. PMID: 18489163

10

Eugenosedin-A prevents hyperglycaemia, hyperlipidaemia and lipid peroxidation in C57BL/6J mice fed a high-fat diet.

Shen KP, Lin HL, Hsieh SL, Kwan AL, Chen IJ, Wu BN. Shen KP, et al. Among authors: wu bn. J Pharm Pharmacol. 2009 Apr;61(4):517-25. doi: 10.1211/jpp/61.04.0015. J Pharm Pharmacol. 2009. PMID: 19298700

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