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Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures.
Zafferani M, Haddad C, Luo L, Davila-Calderon J, Chiu LY, Mugisha CS, Monaghan AG, Kennedy AA, Yesselman JD, Gifford RJ, Tai AW, Kutluay SB, Li ML, Brewer G, Tolbert BS, Hargrove AE. Zafferani M, et al. Among authors: mugisha cs. Sci Adv. 2021 Nov 26;7(48):eabl6096. doi: 10.1126/sciadv.abl6096. Epub 2021 Nov 26. Sci Adv. 2021. PMID: 34826236 Free PMC article.
CARD8 is an inflammasome sensor for HIV-1 protease activity.
Wang Q, Gao H, Clark KM, Mugisha CS, Davis K, Tang JP, Harlan GH, DeSelm CJ, Presti RM, Kutluay SB, Shan L. Wang Q, et al. Among authors: mugisha cs. Science. 2021 Mar 19;371(6535):eabe1707. doi: 10.1126/science.abe1707. Epub 2021 Feb 4. Science. 2021. PMID: 33542150 Free PMC article.
Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell.
Puray-Chavez M, LaPak KM, Schrank TP, Elliott JL, Bhatt DP, Agajanian MJ, Jasuja R, Lawson DQ, Davis K, Rothlauf PW, Jo H, Lee N, Tenneti K, Eschbach JE, Mugisha CS, Vuong HR, Bailey AL, Hayes DN, Whelan SPJ, Horani A, Brody SL, Goldfarb D, Major MB, Kutluay SB. Puray-Chavez M, et al. Among authors: mugisha cs. bioRxiv [Preprint]. 2021 Mar 1:2021.03.01.433431. doi: 10.1101/2021.03.01.433431. bioRxiv. 2021. Update in: Cell Rep. 2021 Jul 13;36(2):109364. doi: 10.1016/j.celrep.2021.109364 PMID: 33688646 Free PMC article. Updated. Preprint.