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519 results

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Page 1
Preclinical characterization of AB-506, an inhibitor of HBV replication targeting the viral core protein.
Mani N, Cole AG, Phelps JR, Ardzinski A, Burns R, Chiu T, Cuconati A, Dorsey BD, Evangelista E, Fan K, Guo F, Harasym TO, Kadhim S, Kowalski R, Kultgen SG, Lee ACH, Li AH, Majeski SA, Miller A, Pasetka C, Reid SP, Rijnbrand R, Micolochick Steuer HM, Stever K, Tang S, Teng X, Wang X, Sofia MJ. Mani N, et al. Among authors: kowalski r. Antiviral Res. 2022 Jan;197:105211. doi: 10.1016/j.antiviral.2021.105211. Epub 2021 Nov 23. Antiviral Res. 2022. PMID: 34826506
Structure-Activity Relationships and Discovery of (S)-5-(tert-Butyl)-11-(difluoromethoxy)-9-methoxy-2-oxo-1,2,5,6-tetrahydropyrido[2',1':2,3]imidazo[4,5-h]quinoline-3-carboxylic Acid (AB-161), a Novel Orally Available and Liver-Centric HBV RNA Destabilizer.
Gotchev D, Chen S, Dugan B, Dorsey BD, Wang X, Sheraz M, Kowalski R, Liu F, Tang S, Chiu T, Harasym T, Graves IE, Thi EP, Mason JD, Overholt N, Dugyala R, Lam AM, Cole AG, Sofia MJ. Gotchev D, et al. Among authors: kowalski r. J Med Chem. 2024 Nov 28;67(22):20467-20494. doi: 10.1021/acs.jmedchem.4c01928. Epub 2024 Nov 8. J Med Chem. 2024. PMID: 39513566
Biological characterization of AB-343, a novel and potent SARS-CoV-2 Mpro inhibitor with pan-coronavirus activity.
McGovern-Gooch KR, Mani N, Gotchev D, Ardzinski A, Kowalski R, Sheraz M, Micolochick Steuer HM, Tercero B, Wang X, Wasserman A, Chen CY, von König K, Maskos K, Prasad A, Blaesse M, Bergmann A, Konz Makino DL, Fan KY, Kultgen SG, Lindstrom A, Nguyen D, Vega M, Wang X, Bracci N, Weiss SR, Cole AG, Lam AM, Cuconati A, Sofia MJ. McGovern-Gooch KR, et al. Among authors: kowalski r. Antiviral Res. 2024 Dec;232:106038. doi: 10.1016/j.antiviral.2024.106038. Epub 2024 Nov 20. Antiviral Res. 2024. PMID: 39577571
Time to Command-Following and Outcomes After Traumatic Brain Injury.
Snider SB, Deng H, Hammond FM, Kowalski RG, Walker WC, Zafonte RD, Okonkwo DO, Giacino JT, Puccio AM, Bodien YG. Snider SB, et al. Among authors: kowalski rg. JAMA Netw Open. 2024 Dec 2;7(12):e2449928. doi: 10.1001/jamanetworkopen.2024.49928. JAMA Netw Open. 2024. PMID: 39656462 Free PMC article.
Unidirectional ray polaritons in twisted asymmetric stacks.
Álvarez-Cuervo J, Obst M, Dixit S, Carini G, F Tresguerres-Mata AI, Lanza C, Terán-García E, Álvarez-Pérez G, Álvarez-Tomillo LF, Diaz-Granados K, Kowalski R, Senerath AS, Mueller NS, Herrer L, De Teresa JM, Wasserroth S, Klopf JM, Beechem T, Wolf M, Eng LM, Folland TG, Tarazaga Martín-Luengo A, Martín-Sánchez J, Kehr SC, Nikitin AY, Caldwell JD, Alonso-González P, Paarmann A. Álvarez-Cuervo J, et al. Among authors: kowalski r. Nat Commun. 2024 Oct 19;15(1):9042. doi: 10.1038/s41467-024-52750-3. Nat Commun. 2024. PMID: 39426947 Free PMC article.
Stability and Dynamics of Zeolite-Confined Gold Nanoclusters.
Sonti S, Sun C, Chen Z, Kowalski RM, Kowalski JS, Donadio D, Ahn SH, Kulkarni AR. Sonti S, et al. Among authors: kowalski rm. J Chem Theory Comput. 2024 Sep 12;20(18):8261-9. doi: 10.1021/acs.jctc.4c00978. Online ahead of print. J Chem Theory Comput. 2024. PMID: 39264121 Free PMC article.
519 results