Wells SA - Search Results

1

Structure and in silico simulations of a cold-active esterase reveals its prime cold-adaptation mechanism.

Noby N, Auhim HS, Winter S, Worthy HL, Embaby AM, Saeed H, Hussein A, Pudney CR, Rizkallah PJ, Wells SA, Jones DD. Noby N, et al. Among authors: wells sa. Open Biol. 2021 Dec;11(12):210182. doi: 10.1098/rsob.210182. Epub 2021 Dec 1. Open Biol. 2021. PMID: 34847772 Free PMC article.

2

A complete thermodynamic analysis of enzyme turnover links the free energy landscape to enzyme catalysis.

Jones HBL, Wells SA, Prentice EJ, Kwok A, Liang LL, Arcus VL, Pudney CR. Jones HBL, et al. Among authors: wells sa. FEBS J. 2017 Sep;284(17):2829-2842. doi: 10.1111/febs.14152. Epub 2017 Jul 25. FEBS J. 2017. PMID: 28650586 Free article.

3

Exposing the Interplay Between Enzyme Turnover, Protein Dynamics, and the Membrane Environment in Monoamine Oxidase B.

Jones HBL, Crean RM, Mullen A, Kendrick EG, Bull SD, Wells SA, Carbery DR, MacMillan F, van der Kamp MW, Pudney CR. Jones HBL, et al. Among authors: wells sa. Biochemistry. 2019 May 7;58(18):2362-2372. doi: 10.1021/acs.biochem.9b00213. Epub 2019 Apr 23. Biochemistry. 2019. PMID: 30964996

4

Monoclonal antibody stability can be usefully monitored using the excitation-energy-dependent fluorescence edge-shift.

Knight MJ, Woolley RE, Kwok A, Parsons S, Jones HBL, Gulácsy CE, Phaal P, Kassaar O, Dawkins K, Rodriguez E, Marques A, Bowsher L, Wells SA, Watts A, van den Elsen JMH, Turner A, O'Hara J, Pudney CR. Knight MJ, et al. Among authors: wells sa. Biochem J. 2020 Sep 30;477(18):3599-3612. doi: 10.1042/BCJ20200580. Biochem J. 2020. PMID: 32869839 Free PMC article.

5

Structure and Function in Homodimeric Enzymes: Simulations of Cooperative and Independent Functional Motions.

Wells SA, van der Kamp MW, McGeagh JD, Mulholland AJ. Wells SA, et al. PLoS One. 2015 Aug 4;10(8):e0133372. doi: 10.1371/journal.pone.0133372. eCollection 2015. PLoS One. 2015. PMID: 26241964 Free PMC article.

6

Salt bridge impact on global rigidity and thermostability in thermophilic citrate synthase.

McManus TJ, Wells SA, Walker AB. McManus TJ, et al. Among authors: wells sa. Phys Biol. 2019 Nov 8;17(1):016002. doi: 10.1088/1478-3975/ab2b5c. Phys Biol. 2019. PMID: 31220825

7

Defining the flexibility window in ordered aluminosilicate zeolites.

Wells SA, Leung KM, Edwards PP, Tucker MG, Sartbaeva A. Wells SA, et al. R Soc Open Sci. 2017 Sep 27;4(9):170757. doi: 10.1098/rsos.170757. eCollection 2017 Sep. R Soc Open Sci. 2017. PMID: 28989777 Free PMC article.

8

Pressure-induced symmetry changes in body-centred cubic zeolites.

Nearchou A, Cornelius MU, Jones ZL, Collings IE, Wells SA, Raithby PR, Sartbaeva A. Nearchou A, et al. Among authors: wells sa. R Soc Open Sci. 2019 Jul 24;6(7):182158. doi: 10.1098/rsos.182158. eCollection 2019 Jul. R Soc Open Sci. 2019. PMID: 31417704 Free PMC article.

9

Constrained geometric simulation of diffusive motion in proteins.

Wells S, Menor S, Hespenheide B, Thorpe MF. Wells S, et al. Phys Biol. 2005 Nov 9;2(4):S127-36. doi: 10.1088/1478-3975/2/4/S07. Phys Biol. 2005. PMID: 16280618

10

Flexibility windows in faujasite with explicit water and methanol extra-framework content.

Wells SA, Leung KM, Edwards PP, Sartbaeva A. Wells SA, et al. Dalton Trans. 2015 Apr 7;44(13):5978-84. doi: 10.1039/c4dt03150d. Dalton Trans. 2015. PMID: 25470761 Free article.

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