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Page 1
Checkpoint Inhibition Reduces the Threshold for Drug-Specific T-Cell Priming and Increases the Incidence of Sulfasalazine Hypersensitivity.
Hammond S, Olsson-Brown A, Grice S, Gibson A, Gardner J, Castrejón-Flores JL, Jolly C, Fisher BA, Steven N, Betts C, Pirmohamed M, Meng X, Naisbitt DJ. Hammond S, et al. Among authors: castrejon flores jl. Toxicol Sci. 2022 Feb 28;186(1):58-69. doi: 10.1093/toxsci/kfab144. Toxicol Sci. 2022. PMID: 34850240 Free PMC article.
Up-Regulation of T-Cell Activation MicroRNAs in Drug-Specific CD4+ T-Cells from Hypersensitive Patients.
Monroy-Arreola A, Durán-Figueroa NV, Méndez-Flores S, Domínguez-Cherit J, Watkinson J, Badillo-Corona JA, Whitaker P, Naisbitt DJ, Castrejón-Flores JL. Monroy-Arreola A, et al. Among authors: castrejon flores jl. Chem Res Toxicol. 2018 Jun 18;31(6):454-461. doi: 10.1021/acs.chemrestox.7b00330. Epub 2018 May 16. Chem Res Toxicol. 2018. PMID: 29644860
Extracellular Vesicles from Human Plasma Show a Distinctive Proteome and miRNome Profile in Patients with Severe Cutaneous Adverse Reactions.
Salinas-Jaramillo O, Monroy-Arreola A, Herrera-Noreña S, Guzmán-Ortiz AL, Hernández-Hernández A, Méndez-Flores S, Domínguez-Cherit J, Duran-Figueroa NV, Naisbitt DJ, Cortes-Reynosa P, Perez Salazar E, Quezada H, Castrejón-Flores JL. Salinas-Jaramillo O, et al. Among authors: castrejon flores jl. Chem Res Toxicol. 2021 Jul 19;34(7):1738-1748. doi: 10.1021/acs.chemrestox.1c00047. Epub 2021 Jun 18. Chem Res Toxicol. 2021. PMID: 34142820
Advances in Our Understanding of the Interaction of Drugs with T-cells: Implications for the Discovery of Biomarkers in Severe Cutaneous Drug Reactions.
Hernandez-Jaimes OA, Cazares-Olvera DV, Line J, Moreno-Eutimio MA, Gómez-Castro CZ, Naisbitt DJ, Castrejón-Flores JL. Hernandez-Jaimes OA, et al. Among authors: castrejon flores jl. Chem Res Toxicol. 2022 Jul 18;35(7):1162-1183. doi: 10.1021/acs.chemrestox.1c00434. Epub 2022 Jun 15. Chem Res Toxicol. 2022. PMID: 35704769 Review.
Involvement of conformational isomerism in the complexity of the crystal network of 1-(4-nitrophenyl)-1H-1,3-benzimidazole derivatives driven by C-H...A (A = NO2, Npy and π) and orthogonal Npy...NO2 and ONO...Csp2 interactions.
García-Aranda MI, Gómez-Castro CZ, García-Báez EV, Gómez YGY, Castrejón-Flores JL, Padilla-Martínez II. García-Aranda MI, et al. Among authors: castrejon flores jl. Acta Crystallogr C Struct Chem. 2018 Apr 1;74(Pt 4):428-436. doi: 10.1107/S2053229618003406. Epub 2018 Mar 7. Acta Crystallogr C Struct Chem. 2018. PMID: 29620026 Free PMC article.
Efficient Editing of the Nuclear APT Reporter Gene in Chlamydomonas reinhardtii via Expression of a CRISPR-Cas9 Module.
Guzmán-Zapata D, Sandoval-Vargas JM, Macedo-Osorio KS, Salgado-Manjarrez E, Castrejón-Flores JL, Oliver-Salvador MDC, Durán-Figueroa NV, Nogué F, Badillo-Corona JA. Guzmán-Zapata D, et al. Among authors: castrejon flores jl. Int J Mol Sci. 2019 Mar 12;20(5):1247. doi: 10.3390/ijms20051247. Int J Mol Sci. 2019. PMID: 30871076 Free PMC article.
Anti-inflammatory effect and inhibition of nitric oxide production by targeting COXs and iNOS enzymes with the 1,2-diphenylbenzimidazole pharmacophore.
García-Aranda MI, Gonzalez-Padilla JE, Gómez-Castro CZ, Gómez-Gómez YM, Rosales-Hernández MC, García-Báez EV, Franco-Hernández MO, Castrejón-Flores JL, Padilla-Martínez II. García-Aranda MI, et al. Among authors: castrejon flores jl. Bioorg Med Chem. 2020 May 1;28(9):115427. doi: 10.1016/j.bmc.2020.115427. Epub 2020 Mar 21. Bioorg Med Chem. 2020. PMID: 32205045
12 results