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KAT6A and ENL Form an Epigenetic Transcriptional Control Module to Drive Critical Leukemogenic Gene-Expression Programs.
Yan F, Li J, Milosevic J, Petroni R, Liu S, Shi Z, Yuan S, Reynaga JM, Qi Y, Rico J, Yu S, Liu Y, Rokudai S, Palmisiano N, Meyer SE, Sung PJ, Wan L, Lan F, Garcia BA, Stanger BZ, Sykes DB, Blanco MA. Yan F, et al. Among authors: blanco ma. Cancer Discov. 2022 Mar 1;12(3):792-811. doi: 10.1158/2159-8290.CD-20-1459. Cancer Discov. 2022. PMID: 34853079 Free PMC article.
Combined epigenetic and metabolic treatments overcome differentiation blockade in acute myeloid leukemia.
Zee BM, Poels KE, Yao CH, Kawabata KC, Wu G, Duy C, Jacobus WD, Senior E, Endress JE, Jambhekar A, Lovitch SB, Ma J, Dhall A, Harris IS, Blanco MA, Sykes DB, Licht JD, Weinstock DM, Melnick A, Haigis MC, Michor F, Shi Y. Zee BM, et al. Among authors: blanco ma, ma j. iScience. 2021 May 25;24(6):102651. doi: 10.1016/j.isci.2021.102651. eCollection 2021 Jun 25. iScience. 2021. PMID: 34151238 Free PMC article.
Chromatin-state barriers enforce an irreversible mammalian cell fate decision.
Blanco MA, Sykes DB, Gu L, Wu M, Petroni R, Karnik R, Wawer M, Rico J, Li H, Jacobus WD, Jambhekar A, Cheloufi S, Meissner A, Hochedlinger K, Scadden DT, Shi Y. Blanco MA, et al. Cell Rep. 2021 Nov 9;37(6):109967. doi: 10.1016/j.celrep.2021.109967. Cell Rep. 2021. PMID: 34758323 Free article.
Regulation of chromatin accessibility by the histone chaperone CAF-1 sustains lineage fidelity.
Franklin R, Guo Y, He S, Chen M, Ji F, Zhou X, Frankhouser D, Do BT, Chiem C, Jang M, Blanco MA, Vander Heiden MG, Rockne RC, Ninova M, Sykes DB, Hochedlinger K, Lu R, Sadreyev RI, Murn J, Volk A, Cheloufi S. Franklin R, et al. Among authors: blanco ma. Nat Commun. 2022 Apr 29;13(1):2350. doi: 10.1038/s41467-022-29730-6. Nat Commun. 2022. PMID: 35487911 Free PMC article.
Protection of Regulatory T Cells from Fragility and Inactivation in the Tumor Microenvironment.
Zhang H, Tomar VS, Li J, Basavaraja R, Yan F, Gui J, McBrearty N, Costich TL, Beiting DP, Blanco MA, Conejo-Garcia JR, Saggu G, Berger A, Nefedova Y, Gabrilovich DI, Fuchs SY. Zhang H, et al. Among authors: blanco ma. Cancer Immunol Res. 2022 Dec 2;10(12):1490-1505. doi: 10.1158/2326-6066.CIR-22-0295. Cancer Immunol Res. 2022. PMID: 36255418 Free PMC article.
A multivalent engagement of ENL with MOZ.
Becht DC, Selvam K, Lachance C, Côté V, Li K, Nguyen MC, Pareek A, Shi X, Wen H, Blanco MA, Côté J, Kutateladze TG. Becht DC, et al. Among authors: blanco ma. Nat Struct Mol Biol. 2025 Jan 10. doi: 10.1038/s41594-024-01455-8. Online ahead of print. Nat Struct Mol Biol. 2025. PMID: 39794553
165 results