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Novel agonist and antagonist radioligands for the GLP-2 receptor. Useful tools for studies of basic GLP-2 receptor pharmacology.
Gadgaard S, van der Velden WJC, Schiellerup SP, Hunt JE, Gabe MBN, Windeløv JA, Boer GA, Kissow H, Ørskov C, Holst JJ, Hartmann B, Rosenkilde MM. Gadgaard S, et al. Among authors: boer ga. Br J Pharmacol. 2022 May;179(9):1998-2015. doi: 10.1111/bph.15766. Epub 2022 Jan 11. Br J Pharmacol. 2022. PMID: 34855984 Free PMC article.
GIP and GLP-2 together improve bone turnover in humans supporting GIPR-GLP-2R co-agonists as future osteoporosis treatment.
Gabe MBN, Skov-Jeppesen K, Gasbjerg LS, Schiellerup SP, Martinussen C, Gadgaard S, Boer GA, Oeke J, Torz LJ, Veedfald S, Svane MS, Bojsen-Møller KN, Madsbad S, Holst JJ, Hartmann B, Rosenkilde MM. Gabe MBN, et al. Among authors: boer ga. Pharmacol Res. 2022 Feb;176:106058. doi: 10.1016/j.phrs.2022.106058. Epub 2022 Jan 4. Pharmacol Res. 2022. PMID: 34995796 Clinical Trial.
Enteroendocrine K Cells Exert Complementary Effects to Control Bone Quality and Mass in Mice.
Gobron B, Bouvard B, Vyavahare S, Blom LV, Pedersen KK, Windeløv JA, Boer GA, Harada N, Zhang S, Shimazu-Kuwahara S, Wice B, Inagaki N, Legrand E, Flatt PR, Chappard D, Hartmann B, Holst JJ, Rosenkilde MM, Irwin N, Mabilleau G. Gobron B, et al. Among authors: boer ga. J Bone Miner Res. 2020 Jul;35(7):1363-1374. doi: 10.1002/jbmr.4004. Epub 2020 Mar 24. J Bone Miner Res. 2020. PMID: 32155286 Free article.
Searching for the physiological role of glucose-dependent insulinotropic polypeptide.
Holst JJ, Windeløv JA, Boer GA, Pedersen J, Svendsen B, Christensen M, Torekov S, Asmar M, Hartmann B, Nissen A. Holst JJ, et al. Among authors: boer ga. J Diabetes Investig. 2016 Apr;7 Suppl 1(Suppl 1):8-12. doi: 10.1111/jdi.12488. Epub 2016 Apr 18. J Diabetes Investig. 2016. PMID: 27186349 Free PMC article. Review.
Age-dependent transition from islet insulin hypersecretion to hyposecretion in mice with the long QT-syndrome loss-of-function mutation Kcnq1-A340V.
Lubberding AF, Zhang J, Lundh M, Nielsen TS, Søndergaard MS, Villadsen M, Skovhøj EZ, Boer GA, Hansen JB, Thomsen MB, Treebak JT, Holst JJ, Kanters JK, Mandrup-Poulsen T, Jespersen T, Emanuelli B, Torekov SS. Lubberding AF, et al. Among authors: boer ga. Sci Rep. 2021 Jun 10;11(1):12253. doi: 10.1038/s41598-021-90452-8. Sci Rep. 2021. PMID: 34112814 Free PMC article.
Guideline implementation, drug sequencing, and quality of care in heart failure: design and rationale of TITRATE-HF.
Clephas PRD, Malgie J, Schaap J, Koudstaal S, Emans M, Linssen GCM, de Boer GA, van Heerebeek L, Borleffs CJW, Manintveld OC, van Empel V, van Wijk S, van den Heuvel M, da Fonseca C, Damman K, van Ramshorst J, van Kimmenade R, van de Ven ART, Tio RA, van Veghel D, Asselbergs FW, de Boer RA, van der Meer P, Greene SJ, Brunner-La Rocca HP, Brugts JJ. Clephas PRD, et al. Among authors: de boer ga. ESC Heart Fail. 2024 Feb;11(1):550-559. doi: 10.1002/ehf2.14604. Epub 2023 Dec 8. ESC Heart Fail. 2024. PMID: 38064176 Free PMC article.
13 results