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DNA-dependent protein kinase catalytic subunit functions in metastasis and influences survival in advanced-stage laryngeal squamous cell carcinoma.
He SS, Chen Y, Shen XM, Wang HZ, Sun P, Dong J, Guo GF, Chen JG, Xia LP, Hu PL, Qiu HJ, Liu SS, Zhou YX, Wang W, Hu WH, Cai XY. He SS, et al. Among authors: sun p. J Cancer. 2017 Jul 22;8(12):2410-2416. doi: 10.7150/jca.20069. eCollection 2017. J Cancer. 2017. PMID: 28819445 Free PMC article.
Methods: We conducted a retrospective study of 208 patients with advanced-stage LSCC treated at Sun Yat-sen University Cancer Center, Guangzhou, China. We assessed DNA-PKcs and p16INK4a (p16) status using immunohistochemistry. ...High DNA-PKcs expression was significantly …
Methods: We conducted a retrospective study of 208 patients with advanced-stage LSCC treated at Sun Yat-sen University Cancer Center, …
Loss of LKB1 Expression Decreases the Survival and Promotes Laryngeal Cancer Metastasis.
He SS, Chen Y, Wang HZ, Shen XM, Sun P, Dong J, Liao XB, Guo GF, Chen JG, Xia LP, Hu PL, Qiu HJ, Liu SS, Zhou YX, Wang W, Hu WH, Cai XY. He SS, et al. Among authors: sun p. J Cancer. 2017 Sep 30;8(17):3548-3554. doi: 10.7150/jca.20535. eCollection 2017. J Cancer. 2017. PMID: 29151940 Free PMC article.
Low LKB1 expression was associated with a significantly shorter OS and DMFS than high LKB1 expression (P = 0.041 and 0.028, respectively; log-rank test), and there was a poorer OS in the p16-positive than p16-negative group. ...Multivariate survival analysis indicated that …
Low LKB1 expression was associated with a significantly shorter OS and DMFS than high LKB1 expression (P = 0.041 and 0.028, respectiv …
7,924 results