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Keratinocyte differentiation antigen-specific T cells in immune checkpoint inhibitor-treated NSCLC patients are associated with improved survival.
Berner F, Niederer R, Luimstra JJ, Pop OT, Jochum AK, Purde MT, Hasan Ali O, Bomze D, Bauer J, Freudenmann LK, Marcu A, Wolfschmitt EM, Haen S, Gross T, Dubbelaar ML, Abdou MT, Baumgaertner P, Appenzeller C, Cicin-Sain C, Lenz T, Speiser DE, Ludewig B, Driessen C, Jörger M, Früh M, Jochum W, Cozzio A, Rammensee HG, Walz J, Neefjes J, Flatz L. Berner F, et al. Among authors: neefjes j. Oncoimmunology. 2021 Nov 27;10(1):2006893. doi: 10.1080/2162402X.2021.2006893. eCollection 2021. Oncoimmunology. 2021. PMID: 34858733 Free PMC article.
Cross-presentation of glycoprotein 96-associated antigens on major histocompatibility complex class I molecules requires receptor-mediated endocytosis.
Singh-Jasuja H, Toes RE, Spee P, Münz C, Hilf N, Schoenberger SP, Ricciardi-Castagnoli P, Neefjes J, Rammensee HG, Arnold-Schild D, Schild H. Singh-Jasuja H, et al. Among authors: neefjes j. J Exp Med. 2000 Jun 5;191(11):1965-74. doi: 10.1084/jem.191.11.1965. J Exp Med. 2000. PMID: 10839811 Free PMC article.
Association of Checkpoint Inhibitor-Induced Toxic Effects With Shared Cancer and Tissue Antigens in Non-Small Cell Lung Cancer.
Berner F, Bomze D, Diem S, Ali OH, Fässler M, Ring S, Niederer R, Ackermann CJ, Baumgaertner P, Pikor N, Cruz CG, van de Veen W, Akdis M, Nikolaev S, Läubli H, Zippelius A, Hartmann F, Cheng HW, Hönger G, Recher M, Goldman J, Cozzio A, Früh M, Neefjes J, Driessen C, Ludewig B, Hegazy AN, Jochum W, Speiser DE, Flatz L. Berner F, et al. Among authors: neefjes j. JAMA Oncol. 2019 Jul 1;5(7):1043-1047. doi: 10.1001/jamaoncol.2019.0402. JAMA Oncol. 2019. PMID: 31021392 Free PMC article. Clinical Trial.
Opportunities for Small Molecules in Cancer Immunotherapy.
van der Zanden SY, Luimstra JJ, Neefjes J, Borst J, Ovaa H. van der Zanden SY, et al. Among authors: neefjes j. Trends Immunol. 2020 Jun;41(6):493-511. doi: 10.1016/j.it.2020.04.004. Epub 2020 May 4. Trends Immunol. 2020. PMID: 32381382 Review.
Autoreactive napsin A-specific T cells are enriched in lung tumors and inflammatory lung lesions during immune checkpoint blockade.
Berner F, Bomze D, Lichtensteiger C, Walter V, Niederer R, Hasan Ali O, Wyss N, Bauer J, Freudenmann LK, Marcu A, Wolfschmitt EM, Haen S, Gross T, Abdou MT, Diem S, Knöpfli S, Sinnberg T, Hofmeister K, Cheng HW, Toma M, Klümper N, Purde MT, Pop OT, Jochum AK, Pascolo S, Joerger M, Früh M, Jochum W, Rammensee HG, Läubli H, Hölzel M, Neefjes J, Walz J, Flatz L. Berner F, et al. Among authors: neefjes j. Sci Immunol. 2022 Sep 2;7(75):eabn9644. doi: 10.1126/sciimmunol.abn9644. Epub 2022 Sep 2. Sci Immunol. 2022. PMID: 36054337
Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy.
Logtenberg MEW, Jansen JHM, Raaben M, Toebes M, Franke K, Brandsma AM, Matlung HL, Fauster A, Gomez-Eerland R, Bakker NAM, van der Schot S, Marijt KA, Verdoes M, Haanen JBAG, van den Berg JH, Neefjes J, van den Berg TK, Brummelkamp TR, Leusen JHW, Scheeren FA, Schumacher TN. Logtenberg MEW, et al. Among authors: neefjes j. Nat Med. 2019 Apr;25(4):612-619. doi: 10.1038/s41591-019-0356-z. Epub 2019 Mar 4. Nat Med. 2019. PMID: 30833751 Free PMC article.
350 results