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Assembly mechanism of the CARMA1-BCL10-MALT1-TRAF6 signalosome.
David L, Li Y, Ma J, Garner E, Zhang X, Wu H. David L, et al. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1499-1504. doi: 10.1073/pnas.1721967115. Epub 2018 Jan 30. Proc Natl Acad Sci U S A. 2018. PMID: 29382759 Free PMC article.
Homogeneous Oligomers of Pro-apoptotic BAX Reveal Structural Determinants of Mitochondrial Membrane Permeabilization.
Hauseman ZJ, Harvey EP, Newman CE, Wales TE, Bucci JC, Mintseris J, Schweppe DK, David L, Fan L, Cohen DT, Herce HD, Mourtada R, Ben-Nun Y, Bloch NB, Hansen SB, Wu H, Gygi SP, Engen JR, Walensky LD. Hauseman ZJ, et al. Among authors: david l. Mol Cell. 2020 Jul 2;79(1):68-83.e7. doi: 10.1016/j.molcel.2020.05.029. Epub 2020 Jun 12. Mol Cell. 2020. PMID: 32533918 Free PMC article.
Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes.
Robert Hollingsworth L, David L, Li Y, Griswold AR, Ruan J, Sharif H, Fontana P, Orth-He EL, Fu TM, Bachovchin DA, Wu H. Robert Hollingsworth L, et al. Among authors: david l. Nat Commun. 2021 Jan 8;12(1):189. doi: 10.1038/s41467-020-20320-y. Nat Commun. 2021. PMID: 33420033 Free PMC article.
ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D.
Du G, Healy LB, David L, Walker C, El-Baba TJ, Lutomski CA, Goh B, Gu B, Pi X, Devant P, Fontana P, Dong Y, Ma X, Miao R, Balasubramanian A, Puthenveetil R, Banerjee A, Luo HR, Kagan JC, Oh SF, Robinson CV, Lieberman J, Wu H. Du G, et al. Among authors: david l. Nature. 2024 Jun;630(8016):437-446. doi: 10.1038/s41586-024-07373-5. Epub 2024 Apr 10. Nature. 2024. PMID: 38599239 Free PMC article.
1,572 results