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Polymorphisms in cytochrome P450 are associated with extensive efavirenz pharmacokinetics and CNS toxicities in an HIV cohort in Botswana.
Vujkovic M, Bellamy SL, Zuppa AF, Gastonguay MR, Moorthy GS, Ratshaa B, Han X, Steenhoff AP, Mosepele M, Strom BL, Bisson GP, Aplenc R, Gross R. Vujkovic M, et al. Among authors: zuppa af. Pharmacogenomics J. 2018 Sep;18(5):678-688. doi: 10.1038/s41397-018-0028-2. Epub 2018 Jun 1. Pharmacogenomics J. 2018. PMID: 29855606 Free PMC article.
Impact of Efavirenz Metabolism on Loss to Care in Older HIV+ Africans.
Torgersen J, Bellamy SL, Ratshaa B, Han X, Mosepele M, Zuppa AF, Vujkovic M, Steenhoff AP, Bisson GP, Gross R. Torgersen J, et al. Among authors: zuppa af. Eur J Drug Metab Pharmacokinet. 2019 Apr;44(2):179-187. doi: 10.1007/s13318-018-0507-5. Eur J Drug Metab Pharmacokinet. 2019. PMID: 30168000 Free PMC article.
Identification of phenotypes in paediatric patients with acute respiratory distress syndrome: a latent class analysis.
Dahmer MK, Yang G, Zhang M, Quasney MW, Sapru A, Weeks HM, Sinha P, Curley MAQ, Delucchi KL, Calfee CS, Flori H; RESTORE and BALI study investigators; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. Dahmer MK, et al. Lancet Respir Med. 2022 Mar;10(3):289-297. doi: 10.1016/S2213-2600(21)00382-9. Epub 2021 Dec 6. Lancet Respir Med. 2022. PMID: 34883088 Free PMC article. Clinical Trial.
CYP2B6 genotypes and early efavirenz-based HIV treatment outcomes in Botswana.
Gross R, Bellamy SL, Ratshaa B, Han X, Vujkovic M, Aplenc R, Steenhoff AP, Mosepele M, Moorthy G, Zuppa AF, Strom BL, Bisson GP. Gross R, et al. Among authors: zuppa af. AIDS. 2017 Sep 24;31(15):2107-2113. doi: 10.1097/QAD.0000000000001593. AIDS. 2017. PMID: 28692529 Free PMC article.
167 results